| Regular Season: Week 1 |
 49ers |
at |
 Saints |
Monday, September 10, 1990 |
3:00PM |
SF 13, NO 12 |
| Regular Season: Week 2 |
 Redskins |
at |
49ers |
Sunday, September 16, 1990 |
3:00PM |
WAS 13, SF 26 |
| Regular Season: Week 3 |
 Falcons |
at |
49ers |
Sunday, September 23, 1990 |
3:00PM |
ATL 13, SF 19 |
| Regular Season: Week 5 |
49ers |
at |
 Oilers |
Sunday, October 7, 1990 |
3:00PM |
SF 24, HOU 21 |
| Regular Season: Week 6 |
49ers |
at |
Falcons |
Sunday, October 14, 1990 |
3:00PM |
SF 45, ATL 35 |
| Regular Season: Week 7 |
 Steelers |
at |
49ers |
Sunday, October 21, 1990 |
3:00PM |
PIT 7, SF 27 |
| Regular Season: Week 8 |
 Browns |
at |
49ers |
Sunday, October 28, 1990 |
2:00PM |
CLE 17, SF 20 |
| Regular Season: Week 9 |
49ers |
at |
 Packers |
Sunday, November 4, 1990 |
3:00PM |
SF 24, GB 20 |
| Regular Season: Week 10 |
49ers |
at |
 Cowboys |
Sunday, November 11, 1990 |
3:00PM |
SF 24, DAL 6 |
| Regular Season: Week 11 |
 Buccaneers |
at |
49ers |
Sunday, November 18, 1990 |
3:00PM |
TB 7, SF 31 |
| Regular Season: Week 12 |
 Rams |
at |
49ers |
Sunday, November 25, 1990 |
3:00PM |
RAM 28, SF 17 |
| Regular Season: Week 13 |
 Giants |
at |
49ers |
Monday, December 3, 1990 |
3:00PM |
NYG 3, SF 7 |
| Regular Season: Week 14 |
49ers |
at |
 Bengals |
Sunday, December 9, 1990 |
3:00PM |
SF 20, CIN 17 |
| Regular Season: Week 15 |
49ers |
at |
Rams |
Monday, December 17, 1990 |
3:00PM |
SF 26, RAM 10 |
| Regular Season: Week 16 |
Saints |
at |
49ers |
Sunday, December 23, 1990 |
3:00PM |
NO 13, SF 10 |
| Regular Season: Week 17 |
49ers |
at |
 Vikings |
Sunday, December 30, 1990 |
3:00PM |
SF 20, MIN 17 |
| Divisional Playoffs: Week 19 |
Redskins |
at |
49ers |
Saturday, January 12, 1991 |
3:00PM |
WAS 10, SF 28 |
| Conference Championship: Week 20 |
Giants |
at |
49ers |
Sunday, January 20, 1991 |
3:00PM |
NYG 15, SF 13 |