| Regular Season: Week 1 |
 Dolphins |
at |
 Bills |
Sunday, September 1, 1991 |
3:00PM |
MIA 31, BUF 35 |
| Regular Season: Week 2 |
 Steelers |
at |
Bills |
Sunday, September 8, 1991 |
3:00PM |
PIT 34, BUF 52 |
| Regular Season: Week 3 |
Bills |
at |
 Jets |
Sunday, September 15, 1991 |
3:00PM |
BUF 23, NYJ 20 |
| Regular Season: Week 4 |
Bills |
at |
 Buccaneers |
Sunday, September 22, 1991 |
3:00PM |
BUF 17, TB 10 |
| Regular Season: Week 5 |
 Bears |
at |
Bills |
Sunday, September 29, 1991 |
3:00PM |
CHI 20, BUF 35 |
| Regular Season: Week 6 |
Bills |
at |
 Chiefs |
Monday, October 7, 1991 |
3:00PM |
BUF 6, KC 33 |
| Regular Season: Week 7 |
 Colts |
at |
Bills |
Sunday, October 13, 1991 |
3:00PM |
IND 6, BUF 42 |
| Regular Season: Week 8 |
 Bengals |
at |
Bills |
Monday, October 21, 1991 |
3:00PM |
CIN 16, BUF 35 |
| Regular Season: Week 10 |
 Patriots |
at |
Bills |
Sunday, November 3, 1991 |
3:00PM |
NE 17, BUF 22 |
| Regular Season: Week 11 |
Bills |
at |
 Packers |
Sunday, November 10, 1991 |
3:00PM |
BUF 34, GB 24 |
| Regular Season: Week 12 |
Bills |
at |
Dolphins |
Monday, November 18, 1991 |
3:00PM |
BUF 41, MIA 27 |
| Regular Season: Week 13 |
Bills |
at |
Patriots |
Sunday, November 24, 1991 |
3:00PM |
BUF 13, NE 16 |
| Regular Season: Week 14 |
Jets |
at |
Bills |
Sunday, December 1, 1991 |
3:00PM |
NYJ 13, BUF 24 |
| Regular Season: Week 15 |
Bills |
at |
 Raiders |
Sunday, December 8, 1991 |
3:00PM |
BUF 30, RAI 27 |
| Regular Season: Week 16 |
Bills |
at |
Colts |
Sunday, December 15, 1991 |
3:00PM |
BUF 35, IND 7 |
| Regular Season: Week 17 |
 Lions |
at |
Bills |
Sunday, December 22, 1991 |
3:00PM |
DET 17, BUF 14 |
| Divisional Playoffs: Week 19 |
Chiefs |
at |
Bills |
Sunday, January 5, 1992 |
3:00PM |
KC 14, BUF 37 |
| Conference Championship: Week 20 |
 Broncos |
at |
Bills |
Sunday, January 12, 1992 |
3:00PM |
DEN 7, BUF 10 |
| Super Bowl: Week 21 |
 Redskins |
at |
Bills |
Sunday, January 26, 1992 |
3:00PM |
WAS 37, BUF 24 |