| Regular Season: Week 1 |
 Bills |
at |
 Chargers |
Sunday, September 6, 1998 |
3:00PM |
BUF 14, SD 16 |
| Regular Season: Week 2 |
Bills |
at |
 Dolphins |
Sunday, September 13, 1998 |
3:00PM |
BUF 7, MIA 13 |
| Regular Season: Week 3 |
 Rams |
at |
Bills |
Sunday, September 20, 1998 |
3:00PM |
STL 34, BUF 33 |
| Regular Season: Week 5 |
 49ers |
at |
Bills |
Sunday, October 4, 1998 |
3:00PM |
SF 21, BUF 26 |
| Regular Season: Week 6 |
Bills |
at |
 Colts |
Sunday, October 11, 1998 |
3:00PM |
BUF 31, IND 24 |
| Regular Season: Week 7 |
 Jaguars |
at |
Bills |
Sunday, October 18, 1998 |
3:00PM |
JAC 16, BUF 17 |
| Regular Season: Week 8 |
Bills |
at |
 Panthers |
Sunday, October 25, 1998 |
2:00PM |
BUF 30, CAR 14 |
| Regular Season: Week 9 |
Dolphins |
at |
Bills |
Sunday, November 1, 1998 |
3:00PM |
MIA 24, BUF 30 |
| Regular Season: Week 10 |
Bills |
at |
 Jets |
Sunday, November 8, 1998 |
3:00PM |
BUF 12, NYJ 34 |
| Regular Season: Week 11 |
 Patriots |
at |
Bills |
Sunday, November 15, 1998 |
3:00PM |
NE 10, BUF 13 |
| Regular Season: Week 12 |
Colts |
at |
Bills |
Sunday, November 22, 1998 |
3:00PM |
IND 11, BUF 34 |
| Regular Season: Week 13 |
Bills |
at |
Patriots |
Sunday, November 29, 1998 |
3:00PM |
BUF 21, NE 25 |
| Regular Season: Week 14 |
Bills |
at |
 Bengals |
Sunday, December 6, 1998 |
3:00PM |
BUF 33, CIN 20 |
| Regular Season: Week 15 |
 Raiders |
at |
Bills |
Sunday, December 13, 1998 |
3:00PM |
OAK 21, BUF 44 |
| Regular Season: Week 16 |
Jets |
at |
Bills |
Saturday, December 19, 1998 |
3:00PM |
NYJ 17, BUF 10 |
| Regular Season: Week 17 |
Bills |
at |
 Saints |
Sunday, December 27, 1998 |
3:00PM |
BUF 45, NO 33 |
| Wild Card: Week 18 |
Bills |
at |
Dolphins |
Saturday, January 2, 1999 |
3:00PM |
BUF 17, MIA 24 |