| Regular Season: Week 1 |
 Chargers |
at |
 Chiefs |
Monday, September 13, 2010 |
10:15PM |
SD 14, KC 21 |
| Regular Season: Week 2 |
Chiefs |
at |
 Browns |
Sunday, September 19, 2010 |
1:00PM |
KC 16, CLE 14 |
| Regular Season: Week 3 |
 49ers |
at |
Chiefs |
Sunday, September 26, 2010 |
1:00PM |
SF 10, KC 31 |
| Regular Season: Week 5 |
Chiefs |
at |
 Colts |
Sunday, October 10, 2010 |
1:00PM |
KC 9, IND 19 |
| Regular Season: Week 6 |
Chiefs |
at |
 Texans |
Sunday, October 17, 2010 |
1:00PM |
KC 31, HOU 35 |
| Regular Season: Week 7 |
 Jaguars |
at |
Chiefs |
Sunday, October 24, 2010 |
1:00PM |
JAC 20, KC 42 |
| Regular Season: Week 8 |
 Bills |
at |
Chiefs |
Sunday, October 31, 2010 |
1:00PM |
BUF 10, KC 13 |
| Regular Season: Week 9 |
Chiefs |
at |
 Raiders |
Sunday, November 7, 2010 |
4:15PM |
KC 20, OAK 23 |
| Regular Season: Week 10 |
Chiefs |
at |
 Broncos |
Sunday, November 14, 2010 |
4:05PM |
KC 29, DEN 49 |
| Regular Season: Week 11 |
 Cardinals |
at |
Chiefs |
Sunday, November 21, 2010 |
1:00PM |
ARI 13, KC 31 |
| Regular Season: Week 12 |
Chiefs |
at |
 Seahawks |
Sunday, November 28, 2010 |
4:05PM |
KC 42, SEA 24 |
| Regular Season: Week 13 |
Broncos |
at |
Chiefs |
Sunday, December 5, 2010 |
1:00PM |
DEN 6, KC 10 |
| Regular Season: Week 14 |
Chiefs |
at |
Chargers |
Sunday, December 12, 2010 |
4:15PM |
KC 0, SD 31 |
| Regular Season: Week 15 |
Chiefs |
at |
 Rams |
Sunday, December 19, 2010 |
1:00PM |
KC 27, STL 13 |
| Regular Season: Week 16 |
 Titans |
at |
Chiefs |
Sunday, December 26, 2010 |
1:00PM |
TEN 14, KC 34 |
| Regular Season: Week 17 |
Raiders |
at |
Chiefs |
Sunday, January 2, 2011 |
1:00PM |
OAK 31, KC 10 |
| Wild Card: Week 18 |
 Ravens |
at |
Chiefs |
Sunday, January 9, 2011 |
1:00PM |
BAL 30, KC 7 |