| Regular Season: Week 1 |
 Browns |
at |
 Colts |
Sunday, September 6, 1992 |
3:00PM |
CLE 3, IND 14 |
| Regular Season: Week 2 |
 Oilers |
at |
Colts |
Sunday, September 13, 1992 |
3:00PM |
HOU 20, IND 10 |
| Regular Season: Week 3 |
Colts |
at |
 Bills |
Sunday, September 20, 1992 |
3:00PM |
IND 0, BUF 38 |
| Regular Season: Week 5 |
Colts |
at |
 Buccaneers |
Sunday, October 4, 1992 |
3:00PM |
IND 24, TB 14 |
| Regular Season: Week 6 |
 Jets |
at |
Colts |
Sunday, October 11, 1992 |
3:00PM |
NYJ 3, IND 6 |
| Regular Season: Week 7 |
 Chargers |
at |
Colts |
Sunday, October 18, 1992 |
3:00PM |
SD 34, IND 14 |
| Regular Season: Week 8 |
Colts |
at |
 Dolphins |
Sunday, October 25, 1992 |
2:00PM |
IND 31, MIA 20 |
| Regular Season: Week 9 |
Colts |
at |
Chargers |
Sunday, November 1, 1992 |
3:00PM |
IND 0, SD 26 |
| Regular Season: Week 10 |
Dolphins |
at |
Colts |
Sunday, November 8, 1992 |
3:00PM |
MIA 28, IND 0 |
| Regular Season: Week 11 |
 Patriots |
at |
Colts |
Sunday, November 15, 1992 |
3:00PM |
NE 37, IND 34 |
| Regular Season: Week 12 |
Colts |
at |
 Steelers |
Sunday, November 22, 1992 |
3:00PM |
IND 14, PIT 30 |
| Regular Season: Week 13 |
Bills |
at |
Colts |
Sunday, November 29, 1992 |
3:00PM |
BUF 13, IND 16 |
| Regular Season: Week 14 |
Colts |
at |
Patriots |
Sunday, December 6, 1992 |
3:00PM |
IND 6, NE 0 |
| Regular Season: Week 15 |
Colts |
at |
Jets |
Sunday, December 13, 1992 |
3:00PM |
IND 10, NYJ 6 |
| Regular Season: Week 16 |
 Cardinals |
at |
Colts |
Sunday, December 20, 1992 |
3:00PM |
PHO 13, IND 16 |
| Regular Season: Week 17 |
Colts |
at |
 Bengals |
Sunday, December 27, 1992 |
3:00PM |
IND 21, CIN 17 |