| Regular Season: Week 1 |
 Lions |
at |
 Vikings |
Sunday, September 13, 1987 |
3:00PM |
DET 19, MIN 34 |
| Regular Season: Week 2 |
Lions |
at |
 Raiders |
Sunday, September 20, 1987 |
3:00PM |
DET 7, RAI 27 |
| Regular Season: Week 3 |
 Buccaneers |
at |
Lions |
Sunday, October 4, 1987 |
3:00PM |
TB 31, DET 27 |
| Regular Season: Week 4 |
Lions |
at |
 Packers |
Sunday, October 11, 1987 |
3:00PM |
DET 19, GB 16 |
| Regular Season: Week 5 |
 Seahawks |
at |
Lions |
Sunday, October 18, 1987 |
3:00PM |
SEA 37, DET 14 |
| Regular Season: Week 6 |
Packers |
at |
Lions |
Sunday, October 25, 1987 |
2:00PM |
GB 34, DET 33 |
| Regular Season: Week 7 |
Lions |
at |
 Broncos |
Sunday, November 1, 1987 |
3:00PM |
DET 0, DEN 34 |
| Regular Season: Week 8 |
 Cowboys |
at |
Lions |
Sunday, November 8, 1987 |
3:00PM |
DAL 17, DET 27 |
| Regular Season: Week 9 |
Lions |
at |
 Redskins |
Sunday, November 15, 1987 |
3:00PM |
DET 13, WAS 20 |
| Regular Season: Week 10 |
Lions |
at |
 Bears |
Sunday, November 22, 1987 |
3:00PM |
DET 10, CHI 30 |
| Regular Season: Week 11 |
 Chiefs |
at |
Lions |
Thursday, November 26, 1987 |
3:00PM |
KC 27, DET 20 |
| Regular Season: Week 12 |
 Rams |
at |
Lions |
Sunday, December 6, 1987 |
3:00PM |
RAM 37, DET 16 |
| Regular Season: Week 13 |
Lions |
at |
Buccaneers |
Sunday, December 13, 1987 |
3:00PM |
DET 20, TB 10 |
| Regular Season: Week 14 |
Vikings |
at |
Lions |
Sunday, December 20, 1987 |
3:00PM |
MIN 17, DET 14 |
| Regular Season: Week 15 |
Lions |
at |
 Falcons |
Sunday, December 27, 1987 |
3:00PM |
DET 30, ATL 13 |