| Regular Season: Week 1 |
 Lions |
at |
 Saints |
Sunday, September 3, 2000 |
1:00PM |
DET 14, NO 10 |
| Regular Season: Week 2 |
 Redskins |
at |
Lions |
Sunday, September 10, 2000 |
4:15PM |
WAS 10, DET 15 |
| Regular Season: Week 3 |
 Buccaneers |
at |
Lions |
Sunday, September 17, 2000 |
1:00PM |
TB 31, DET 10 |
| Regular Season: Week 4 |
Lions |
at |
 Bears |
Sunday, September 24, 2000 |
1:00PM |
DET 21, CHI 14 |
| Regular Season: Week 5 |
 Vikings |
at |
Lions |
Sunday, October 1, 2000 |
1:00PM |
MIN 31, DET 24 |
| Regular Season: Week 6 |
 Packers |
at |
Lions |
Sunday, October 8, 2000 |
1:00PM |
GB 24, DET 31 |
| Regular Season: Week 8 |
Lions |
at |
Buccaneers |
Thursday, October 19, 2000 |
8:20PM |
DET 28, TB 14 |
| Regular Season: Week 9 |
Lions |
at |
 Colts |
Sunday, October 29, 2000 |
1:00PM |
DET 18, IND 30 |
| Regular Season: Week 10 |
 Dolphins |
at |
Lions |
Sunday, November 5, 2000 |
1:00PM |
MIA 23, DET 8 |
| Regular Season: Week 11 |
 Falcons |
at |
Lions |
Sunday, November 12, 2000 |
1:00PM |
ATL 10, DET 13 |
| Regular Season: Week 12 |
Lions |
at |
 Giants |
Sunday, November 19, 2000 |
1:00PM |
DET 31, NYG 21 |
| Regular Season: Week 13 |
 Patriots |
at |
Lions |
Thursday, November 23, 2000 |
12:30PM |
NE 9, DET 34 |
| Regular Season: Week 14 |
Lions |
at |
Vikings |
Thursday, November 30, 2000 |
8:20PM |
DET 17, MIN 24 |
| Regular Season: Week 15 |
Lions |
at |
Packers |
Sunday, December 10, 2000 |
1:00PM |
DET 13, GB 26 |
| Regular Season: Week 16 |
Lions |
at |
 Jets |
Sunday, December 17, 2000 |
1:00PM |
DET 10, NYJ 7 |
| Regular Season: Week 17 |
Bears |
at |
Lions |
Sunday, December 24, 2000 |
1:00PM |
CHI 23, DET 20 |