| Regular Season: Week 1 |
 Oilers |
at |
 Patriots |
Sunday, September 21, 1975 |
3:00PM |
HOU 7, NE 0 |
| Regular Season: Week 2 |
 Chargers |
at |
Oilers |
Sunday, September 28, 1975 |
3:00PM |
SD 17, HOU 33 |
| Regular Season: Week 3 |
 Bengals |
at |
Oilers |
Sunday, October 5, 1975 |
3:00PM |
CIN 21, HOU 19 |
| Regular Season: Week 4 |
Oilers |
at |
 Browns |
Sunday, October 12, 1975 |
3:00PM |
HOU 40, CLE 10 |
| Regular Season: Week 5 |
 Redskins |
at |
Oilers |
Sunday, October 19, 1975 |
3:00PM |
WAS 10, HOU 13 |
| Regular Season: Week 6 |
 Lions |
at |
Oilers |
Sunday, October 26, 1975 |
2:00PM |
DET 8, HOU 24 |
| Regular Season: Week 7 |
Oilers |
at |
 Chiefs |
Sunday, November 2, 1975 |
3:00PM |
HOU 17, KC 13 |
| Regular Season: Week 8 |
Oilers |
at |
 Steelers |
Sunday, November 9, 1975 |
3:00PM |
HOU 17, PIT 24 |
| Regular Season: Week 9 |
 Dolphins |
at |
Oilers |
Sunday, November 16, 1975 |
3:00PM |
MIA 19, HOU 20 |
| Regular Season: Week 10 |
Steelers |
at |
Oilers |
Monday, November 24, 1975 |
3:00PM |
PIT 32, HOU 9 |
| Regular Season: Week 11 |
Oilers |
at |
Bengals |
Sunday, November 30, 1975 |
3:00PM |
HOU 19, CIN 23 |
| Regular Season: Week 12 |
Oilers |
at |
 49ers |
Sunday, December 7, 1975 |
3:00PM |
HOU 27, SF 13 |
| Regular Season: Week 13 |
Oilers |
at |
 Raiders |
Sunday, December 14, 1975 |
3:00PM |
HOU 27, OAK 26 |
| Regular Season: Week 14 |
Browns |
at |
Oilers |
Sunday, December 21, 1975 |
3:00PM |
CLE 10, HOU 21 |