| Regular Season: Week 1 |
 Oilers |
at |
 Falcons |
Sunday, September 9, 1990 |
3:00PM |
HOU 27, ATL 47 |
| Regular Season: Week 2 |
Oilers |
at |
 Steelers |
Sunday, September 16, 1990 |
3:00PM |
HOU 9, PIT 20 |
| Regular Season: Week 3 |
 Colts |
at |
Oilers |
Sunday, September 23, 1990 |
3:00PM |
IND 10, HOU 24 |
| Regular Season: Week 4 |
Oilers |
at |
 Chargers |
Sunday, September 30, 1990 |
3:00PM |
HOU 17, SD 7 |
| Regular Season: Week 5 |
 49ers |
at |
Oilers |
Sunday, October 7, 1990 |
3:00PM |
SF 24, HOU 21 |
| Regular Season: Week 6 |
 Bengals |
at |
Oilers |
Sunday, October 14, 1990 |
3:00PM |
CIN 17, HOU 48 |
| Regular Season: Week 7 |
 Saints |
at |
Oilers |
Sunday, October 21, 1990 |
3:00PM |
NO 10, HOU 23 |
| Regular Season: Week 8 |
 Jets |
at |
Oilers |
Sunday, October 28, 1990 |
2:00PM |
NYJ 17, HOU 12 |
| Regular Season: Week 9 |
Oilers |
at |
 Rams |
Sunday, November 4, 1990 |
3:00PM |
HOU 13, RAM 17 |
| Regular Season: Week 11 |
Oilers |
at |
 Browns |
Sunday, November 18, 1990 |
3:00PM |
HOU 35, CLE 23 |
| Regular Season: Week 12 |
 Bills |
at |
Oilers |
Monday, November 26, 1990 |
3:00PM |
BUF 24, HOU 27 |
| Regular Season: Week 13 |
Oilers |
at |
 Seahawks |
Sunday, December 2, 1990 |
3:00PM |
HOU 10, SEA 13 |
| Regular Season: Week 14 |
Browns |
at |
Oilers |
Sunday, December 9, 1990 |
3:00PM |
CLE 14, HOU 58 |
| Regular Season: Week 15 |
Oilers |
at |
 Chiefs |
Sunday, December 16, 1990 |
3:00PM |
HOU 27, KC 10 |
| Regular Season: Week 16 |
Oilers |
at |
Bengals |
Sunday, December 23, 1990 |
3:00PM |
HOU 20, CIN 40 |
| Regular Season: Week 17 |
Steelers |
at |
Oilers |
Sunday, December 30, 1990 |
3:00PM |
PIT 14, HOU 34 |
| Wild Card: Week 18 |
Oilers |
at |
Bengals |
Sunday, January 6, 1991 |
3:00PM |
HOU 14, CIN 41 |