| Regular Season: Week 1 |
 Patriots |
at |
 Bills |
Sunday, September 8, 1968 |
3:00PM |
BOS 16, BUF 7 |
| Regular Season: Week 2 |
 Jets |
at |
Patriots |
Sunday, September 22, 1968 |
3:00PM |
NYJ 47, BOS 31 |
| Regular Season: Week 3 |
Patriots |
at |
 Broncos |
Sunday, September 29, 1968 |
3:00PM |
BOS 20, DEN 17 |
| Regular Season: Week 4 |
Patriots |
at |
 Raiders |
Sunday, October 6, 1968 |
3:00PM |
BOS 10, OAK 41 |
| Regular Season: Week 5 |
 Oilers |
at |
Patriots |
Sunday, October 13, 1968 |
3:00PM |
HOU 16, BOS 0 |
| Regular Season: Week 6 |
Bills |
at |
Patriots |
Sunday, October 20, 1968 |
3:00PM |
BUF 6, BOS 23 |
| Regular Season: Week 7 |
Patriots |
at |
Jets |
Sunday, October 27, 1968 |
2:00PM |
BOS 14, NYJ 48 |
| Regular Season: Week 8 |
Broncos |
at |
Patriots |
Sunday, November 3, 1968 |
3:00PM |
DEN 35, BOS 14 |
| Regular Season: Week 9 |
 Chargers |
at |
Patriots |
Sunday, November 10, 1968 |
3:00PM |
SD 27, BOS 17 |
| Regular Season: Week 10 |
Patriots |
at |
 Chiefs |
Sunday, November 17, 1968 |
3:00PM |
BOS 17, KC 31 |
| Regular Season: Week 11 |
 Dolphins |
at |
Patriots |
Sunday, November 24, 1968 |
3:00PM |
MIA 34, BOS 10 |
| Regular Season: Week 12 |
 Bengals |
at |
Patriots |
Sunday, December 1, 1968 |
3:00PM |
CIN 14, BOS 33 |
| Regular Season: Week 13 |
Patriots |
at |
Dolphins |
Sunday, December 8, 1968 |
3:00PM |
BOS 7, MIA 38 |
| Regular Season: Week 14 |
Patriots |
at |
Oilers |
Sunday, December 15, 1968 |
3:00PM |
BOS 17, HOU 45 |