| Regular Season: Week 1 |
 Seahawks |
at |
 Broncos |
Sunday, September 4, 1988 |
3:00PM |
SEA 21, DEN 14 |
| Regular Season: Week 2 |
 Chiefs |
at |
Seahawks |
Sunday, September 11, 1988 |
3:00PM |
KC 10, SEA 31 |
| Regular Season: Week 3 |
Seahawks |
at |
 Chargers |
Sunday, September 18, 1988 |
3:00PM |
SEA 6, SD 17 |
| Regular Season: Week 4 |
 49ers |
at |
Seahawks |
Sunday, September 25, 1988 |
3:00PM |
SF 38, SEA 7 |
| Regular Season: Week 5 |
Seahawks |
at |
 Falcons |
Sunday, October 2, 1988 |
3:00PM |
SEA 31, ATL 20 |
| Regular Season: Week 6 |
Seahawks |
at |
 Browns |
Sunday, October 9, 1988 |
3:00PM |
SEA 16, CLE 10 |
| Regular Season: Week 7 |
 Saints |
at |
Seahawks |
Sunday, October 16, 1988 |
3:00PM |
NO 20, SEA 19 |
| Regular Season: Week 8 |
Seahawks |
at |
 Rams |
Sunday, October 23, 1988 |
3:00PM |
SEA 10, RAM 31 |
| Regular Season: Week 9 |
Chargers |
at |
Seahawks |
Sunday, October 30, 1988 |
2:00PM |
SD 14, SEA 17 |
| Regular Season: Week 10 |
 Bills |
at |
Seahawks |
Sunday, November 6, 1988 |
3:00PM |
BUF 13, SEA 3 |
| Regular Season: Week 11 |
 Oilers |
at |
Seahawks |
Sunday, November 13, 1988 |
3:00PM |
HOU 24, SEA 27 |
| Regular Season: Week 12 |
Seahawks |
at |
Chiefs |
Sunday, November 20, 1988 |
3:00PM |
SEA 24, KC 27 |
| Regular Season: Week 13 |
 Raiders |
at |
Seahawks |
Monday, November 28, 1988 |
3:00PM |
RAI 27, SEA 35 |
| Regular Season: Week 14 |
Seahawks |
at |
 Patriots |
Sunday, December 4, 1988 |
3:00PM |
SEA 7, NE 13 |
| Regular Season: Week 15 |
Broncos |
at |
Seahawks |
Sunday, December 11, 1988 |
3:00PM |
DEN 14, SEA 42 |
| Regular Season: Week 16 |
Seahawks |
at |
Raiders |
Sunday, December 18, 1988 |
3:00PM |
SEA 43, RAI 37 |
| Divisional Playoffs: Week 18 |
Seahawks |
at |
 Bengals |
Saturday, December 31, 1988 |
3:00PM |
SEA 13, CIN 21 |