| Regular Season: Week 1 |
 49ers |
at |
 Vikings |
Sunday, September 8, 1985 |
3:00PM |
SF 21, MIN 28 |
| Regular Season: Week 2 |
 Falcons |
at |
49ers |
Sunday, September 15, 1985 |
3:00PM |
ATL 16, SF 35 |
| Regular Season: Week 3 |
49ers |
at |
 Raiders |
Sunday, September 22, 1985 |
3:00PM |
SF 34, RAI 10 |
| Regular Season: Week 4 |
 Saints |
at |
49ers |
Sunday, September 29, 1985 |
3:00PM |
NO 20, SF 17 |
| Regular Season: Week 5 |
49ers |
at |
Falcons |
Sunday, October 6, 1985 |
3:00PM |
SF 38, ATL 17 |
| Regular Season: Week 6 |
 Bears |
at |
49ers |
Sunday, October 13, 1985 |
3:00PM |
CHI 26, SF 10 |
| Regular Season: Week 7 |
49ers |
at |
 Lions |
Sunday, October 20, 1985 |
3:00PM |
SF 21, DET 23 |
| Regular Season: Week 8 |
49ers |
at |
 Rams |
Sunday, October 27, 1985 |
2:00PM |
SF 28, RAM 14 |
| Regular Season: Week 9 |
 Eagles |
at |
49ers |
Sunday, November 3, 1985 |
3:00PM |
PHI 13, SF 24 |
| Regular Season: Week 10 |
49ers |
at |
 Broncos |
Monday, November 11, 1985 |
3:00PM |
SF 16, DEN 17 |
| Regular Season: Week 11 |
 Chiefs |
at |
49ers |
Sunday, November 17, 1985 |
3:00PM |
KC 3, SF 31 |
| Regular Season: Week 12 |
 Seahawks |
at |
49ers |
Monday, November 25, 1985 |
3:00PM |
SEA 6, SF 19 |
| Regular Season: Week 13 |
49ers |
at |
 Redskins |
Sunday, December 1, 1985 |
3:00PM |
SF 35, WAS 8 |
| Regular Season: Week 14 |
Rams |
at |
49ers |
Monday, December 9, 1985 |
3:00PM |
RAM 27, SF 20 |
| Regular Season: Week 15 |
49ers |
at |
Saints |
Sunday, December 15, 1985 |
3:00PM |
SF 31, NO 19 |
| Regular Season: Week 16 |
 Cowboys |
at |
49ers |
Sunday, December 22, 1985 |
3:00PM |
DAL 16, SF 31 |
| Wild Card: Week 17 |
49ers |
at |
 Giants |
Sunday, December 29, 1985 |
3:00PM |
SF 3, NYG 17 |