| Regular Season: Week 1 |
 49ers |
at |
 Saints |
Sunday, September 4, 1988 |
3:00PM |
SF 34, NO 33 |
| Regular Season: Week 2 |
49ers |
at |
 Giants |
Sunday, September 11, 1988 |
3:00PM |
SF 20, NYG 17 |
| Regular Season: Week 3 |
 Falcons |
at |
49ers |
Sunday, September 18, 1988 |
3:00PM |
ATL 34, SF 17 |
| Regular Season: Week 4 |
49ers |
at |
 Seahawks |
Sunday, September 25, 1988 |
3:00PM |
SF 38, SEA 7 |
| Regular Season: Week 5 |
 Lions |
at |
49ers |
Sunday, October 2, 1988 |
3:00PM |
DET 13, SF 20 |
| Regular Season: Week 6 |
 Broncos |
at |
49ers |
Sunday, October 9, 1988 |
3:00PM |
DEN 16, SF 13 |
| Regular Season: Week 7 |
49ers |
at |
 Rams |
Sunday, October 16, 1988 |
3:00PM |
SF 24, RAM 21 |
| Regular Season: Week 8 |
49ers |
at |
 Bears |
Monday, October 24, 1988 |
3:00PM |
SF 9, CHI 10 |
| Regular Season: Week 9 |
 Vikings |
at |
49ers |
Sunday, October 30, 1988 |
2:00PM |
MIN 21, SF 24 |
| Regular Season: Week 10 |
49ers |
at |
 Cardinals |
Sunday, November 6, 1988 |
3:00PM |
SF 23, PHO 24 |
| Regular Season: Week 11 |
 Raiders |
at |
49ers |
Sunday, November 13, 1988 |
3:00PM |
RAI 9, SF 3 |
| Regular Season: Week 12 |
 Redskins |
at |
49ers |
Monday, November 21, 1988 |
3:00PM |
WAS 21, SF 37 |
| Regular Season: Week 13 |
49ers |
at |
 Chargers |
Sunday, November 27, 1988 |
3:00PM |
SF 48, SD 10 |
| Regular Season: Week 14 |
49ers |
at |
Falcons |
Sunday, December 4, 1988 |
3:00PM |
SF 13, ATL 3 |
| Regular Season: Week 15 |
Saints |
at |
49ers |
Sunday, December 11, 1988 |
3:00PM |
NO 17, SF 30 |
| Regular Season: Week 16 |
Rams |
at |
49ers |
Sunday, December 18, 1988 |
3:00PM |
RAM 38, SF 16 |
| Divisional Playoffs: Week 18 |
Vikings |
at |
49ers |
Sunday, January 1, 1989 |
3:00PM |
MIN 9, SF 34 |
| Conference Championship: Week 19 |
49ers |
at |
Bears |
Sunday, January 8, 1989 |
3:00PM |
SF 28, CHI 3 |
| Super Bowl: Week 20 |
 Bengals |
at |
49ers |
Sunday, January 22, 1989 |
3:00PM |
CIN 16, SF 20 |