| Regular Season: Week 1 |
 49ers |
at |
 Jaguars |
Sunday, September 12, 1999 |
3:00PM |
SF 3, JAC 41 |
| Regular Season: Week 2 |
 Saints |
at |
49ers |
Sunday, September 19, 1999 |
3:00PM |
NO 21, SF 28 |
| Regular Season: Week 3 |
49ers |
at |
 Cardinals |
Monday, September 27, 1999 |
3:00PM |
SF 24, ARI 10 |
| Regular Season: Week 4 |
 Titans |
at |
49ers |
Sunday, October 3, 1999 |
3:00PM |
TEN 22, SF 24 |
| Regular Season: Week 5 |
49ers |
at |
 Rams |
Sunday, October 10, 1999 |
3:00PM |
SF 20, STL 42 |
| Regular Season: Week 6 |
 Panthers |
at |
49ers |
Sunday, October 17, 1999 |
3:00PM |
CAR 31, SF 29 |
| Regular Season: Week 7 |
49ers |
at |
 Vikings |
Sunday, October 24, 1999 |
3:00PM |
SF 16, MIN 40 |
| Regular Season: Week 9 |
 Steelers |
at |
49ers |
Sunday, November 7, 1999 |
3:00PM |
PIT 27, SF 6 |
| Regular Season: Week 10 |
49ers |
at |
Saints |
Sunday, November 14, 1999 |
3:00PM |
SF 6, NO 24 |
| Regular Season: Week 11 |
Rams |
at |
49ers |
Sunday, November 21, 1999 |
3:00PM |
STL 23, SF 7 |
| Regular Season: Week 12 |
 Packers |
at |
49ers |
Monday, November 29, 1999 |
3:00PM |
GB 20, SF 3 |
| Regular Season: Week 13 |
49ers |
at |
 Bengals |
Sunday, December 5, 1999 |
3:00PM |
SF 30, CIN 44 |
| Regular Season: Week 14 |
 Falcons |
at |
49ers |
Sunday, December 12, 1999 |
3:00PM |
ATL 7, SF 26 |
| Regular Season: Week 15 |
49ers |
at |
Panthers |
Saturday, December 18, 1999 |
3:00PM |
SF 24, CAR 41 |
| Regular Season: Week 16 |
 Redskins |
at |
49ers |
Sunday, December 26, 1999 |
3:00PM |
WAS 26, SF 20 |
| Regular Season: Week 17 |
49ers |
at |
Falcons |
Monday, January 3, 2000 |
3:00PM |
SF 29, ATL 34 |