| Regular Season: Week 1 |
 Bears |
at |
 49ers |
Sunday, September 7, 2003 |
4:15PM |
CHI 7, SF 49 |
| Regular Season: Week 2 |
49ers |
at |
 Rams |
Sunday, September 14, 2003 |
1:00PM |
SF 24, STL 27 |
| Regular Season: Week 3 |
 Browns |
at |
49ers |
Sunday, September 21, 2003 |
4:15PM |
CLE 13, SF 12 |
| Regular Season: Week 4 |
49ers |
at |
 Vikings |
Sunday, September 28, 2003 |
1:00PM |
SF 7, MIN 35 |
| Regular Season: Week 5 |
 Lions |
at |
49ers |
Sunday, October 5, 2003 |
4:15PM |
DET 17, SF 24 |
| Regular Season: Week 6 |
49ers |
at |
 Seahawks |
Sunday, October 12, 2003 |
8:30PM |
SF 19, SEA 20 |
| Regular Season: Week 7 |
 Buccaneers |
at |
49ers |
Sunday, October 19, 2003 |
4:15PM |
TB 7, SF 24 |
| Regular Season: Week 8 |
49ers |
at |
 Cardinals |
Sunday, October 26, 2003 |
4:05PM |
SF 13, ARI 16 |
| Regular Season: Week 9 |
Rams |
at |
49ers |
Sunday, November 2, 2003 |
4:15PM |
STL 10, SF 30 |
| Regular Season: Week 11 |
 Steelers |
at |
49ers |
Monday, November 17, 2003 |
9:00PM |
PIT 14, SF 30 |
| Regular Season: Week 12 |
49ers |
at |
 Packers |
Sunday, November 23, 2003 |
1:00PM |
SF 10, GB 20 |
| Regular Season: Week 13 |
49ers |
at |
 Ravens |
Sunday, November 30, 2003 |
1:00PM |
SF 6, BAL 44 |
| Regular Season: Week 14 |
Cardinals |
at |
49ers |
Sunday, December 7, 2003 |
4:05PM |
ARI 14, SF 50 |
| Regular Season: Week 15 |
49ers |
at |
 Bengals |
Sunday, December 14, 2003 |
1:00PM |
SF 38, CIN 41 |
| Regular Season: Week 16 |
49ers |
at |
 Eagles |
Sunday, December 21, 2003 |
4:15PM |
SF 31, PHI 28 |
| Regular Season: Week 17 |
Seahawks |
at |
49ers |
Saturday, December 27, 2003 |
5:00PM |
SEA 24, SF 17 |