| Regular Season: Week 1 |
 Cardinals |
at |
 49ers |
Monday, September 10, 2007 |
10:15PM |
ARI 17, SF 20 |
| Regular Season: Week 2 |
49ers |
at |
 Rams |
Sunday, September 16, 2007 |
1:00PM |
SF 17, STL 16 |
| Regular Season: Week 3 |
49ers |
at |
 Steelers |
Sunday, September 23, 2007 |
1:00PM |
SF 16, PIT 37 |
| Regular Season: Week 4 |
 Seahawks |
at |
49ers |
Sunday, September 30, 2007 |
4:05PM |
SEA 23, SF 3 |
| Regular Season: Week 5 |
 Ravens |
at |
49ers |
Sunday, October 7, 2007 |
4:15PM |
BAL 9, SF 7 |
| Regular Season: Week 7 |
49ers |
at |
 Giants |
Sunday, October 21, 2007 |
1:00PM |
SF 15, NYG 33 |
| Regular Season: Week 8 |
 Saints |
at |
49ers |
Sunday, October 28, 2007 |
4:15PM |
NO 31, SF 10 |
| Regular Season: Week 9 |
49ers |
at |
 Falcons |
Sunday, November 4, 2007 |
1:00PM |
SF 16, ATL 20 |
| Regular Season: Week 10 |
49ers |
at |
Seahawks |
Monday, November 12, 2007 |
8:30PM |
SF 0, SEA 24 |
| Regular Season: Week 11 |
Rams |
at |
49ers |
Sunday, November 18, 2007 |
4:15PM |
STL 13, SF 9 |
| Regular Season: Week 12 |
49ers |
at |
Cardinals |
Sunday, November 25, 2007 |
4:05PM |
SF 37, ARI 31 |
| Regular Season: Week 13 |
49ers |
at |
 Panthers |
Sunday, December 2, 2007 |
1:00PM |
SF 14, CAR 31 |
| Regular Season: Week 14 |
 Vikings |
at |
49ers |
Sunday, December 9, 2007 |
4:05PM |
MIN 27, SF 7 |
| Regular Season: Week 15 |
 Bengals |
at |
49ers |
Saturday, December 15, 2007 |
8:00PM |
CIN 13, SF 20 |
| Regular Season: Week 16 |
 Buccaneers |
at |
49ers |
Sunday, December 23, 2007 |
4:05PM |
TB 19, SF 21 |
| Regular Season: Week 17 |
49ers |
at |
 Browns |
Sunday, December 30, 2007 |
1:00PM |
SF 7, CLE 20 |