| Regular Season: Week 1 |
 Cardinals |
at |
 Bears |
Sunday, September 3, 1978 |
3:00PM |
STL 10, CHI 17 |
| Regular Season: Week 2 |
Bears |
at |
 49ers |
Sunday, September 10, 1978 |
3:00PM |
CHI 16, SF 13 |
| Regular Season: Week 3 |
Bears |
at |
 Lions |
Sunday, September 17, 1978 |
3:00PM |
CHI 19, DET 0 |
| Regular Season: Week 4 |
 Vikings |
at |
Bears |
Monday, September 25, 1978 |
3:00PM |
MIN 24, CHI 20 |
| Regular Season: Week 5 |
 Raiders |
at |
Bears |
Sunday, October 1, 1978 |
3:00PM |
OAK 25, CHI 19 |
| Regular Season: Week 6 |
Bears |
at |
 Packers |
Sunday, October 8, 1978 |
3:00PM |
CHI 14, GB 24 |
| Regular Season: Week 7 |
Bears |
at |
 Broncos |
Monday, October 16, 1978 |
3:00PM |
CHI 7, DEN 16 |
| Regular Season: Week 8 |
Bears |
at |
 Buccaneers |
Sunday, October 22, 1978 |
3:00PM |
CHI 19, TB 33 |
| Regular Season: Week 9 |
Lions |
at |
Bears |
Sunday, October 29, 1978 |
2:00PM |
DET 21, CHI 17 |
| Regular Season: Week 10 |
 Seahawks |
at |
Bears |
Sunday, November 5, 1978 |
3:00PM |
SEA 31, CHI 29 |
| Regular Season: Week 11 |
Bears |
at |
Vikings |
Sunday, November 12, 1978 |
3:00PM |
CHI 14, MIN 17 |
| Regular Season: Week 12 |
 Falcons |
at |
Bears |
Sunday, November 19, 1978 |
3:00PM |
ATL 7, CHI 13 |
| Regular Season: Week 13 |
Buccaneers |
at |
Bears |
Sunday, November 26, 1978 |
3:00PM |
TB 3, CHI 14 |
| Regular Season: Week 14 |
Bears |
at |
 Chargers |
Monday, December 4, 1978 |
3:00PM |
CHI 7, SD 40 |
| Regular Season: Week 15 |
Packers |
at |
Bears |
Sunday, December 10, 1978 |
3:00PM |
GB 0, CHI 14 |
| Regular Season: Week 16 |
Bears |
at |
 Redskins |
Saturday, December 16, 1978 |
3:00PM |
CHI 14, WAS 10 |