| Regular Season: Week 1 |
 Packers |
at |
 Bears |
Sunday, September 6, 1981 |
3:00PM |
GB 16, CHI 9 |
| Regular Season: Week 2 |
Bears |
at |
 49ers |
Sunday, September 13, 1981 |
3:00PM |
CHI 17, SF 28 |
| Regular Season: Week 3 |
 Buccaneers |
at |
Bears |
Sunday, September 20, 1981 |
3:00PM |
TB 17, CHI 28 |
| Regular Season: Week 4 |
 Rams |
at |
Bears |
Monday, September 28, 1981 |
3:00PM |
LA 24, CHI 7 |
| Regular Season: Week 5 |
Bears |
at |
 Vikings |
Sunday, October 4, 1981 |
3:00PM |
CHI 21, MIN 24 |
| Regular Season: Week 6 |
 Redskins |
at |
Bears |
Sunday, October 11, 1981 |
3:00PM |
WAS 24, CHI 7 |
| Regular Season: Week 7 |
Bears |
at |
 Lions |
Monday, October 19, 1981 |
3:00PM |
CHI 17, DET 48 |
| Regular Season: Week 8 |
 Chargers |
at |
Bears |
Sunday, October 25, 1981 |
2:00PM |
SD 17, CHI 20 |
| Regular Season: Week 9 |
Bears |
at |
Buccaneers |
Sunday, November 1, 1981 |
3:00PM |
CHI 10, TB 20 |
| Regular Season: Week 10 |
Bears |
at |
 Chiefs |
Sunday, November 8, 1981 |
3:00PM |
CHI 16, KC 13 |
| Regular Season: Week 11 |
Bears |
at |
Packers |
Sunday, November 15, 1981 |
3:00PM |
CHI 17, GB 21 |
| Regular Season: Week 12 |
Lions |
at |
Bears |
Sunday, November 22, 1981 |
3:00PM |
DET 23, CHI 7 |
| Regular Season: Week 13 |
Bears |
at |
 Cowboys |
Thursday, November 26, 1981 |
3:00PM |
CHI 9, DAL 10 |
| Regular Season: Week 14 |
Vikings |
at |
Bears |
Sunday, December 6, 1981 |
3:00PM |
MIN 9, CHI 10 |
| Regular Season: Week 15 |
Bears |
at |
 Raiders |
Sunday, December 13, 1981 |
3:00PM |
CHI 23, OAK 6 |
| Regular Season: Week 16 |
 Broncos |
at |
Bears |
Sunday, December 20, 1981 |
3:00PM |
DEN 24, CHI 35 |