| Regular Season: Week 1 |
 Broncos |
at |
 Bills |
Sunday, September 20, 1970 |
3:00PM |
DEN 25, BUF 10 |
| Regular Season: Week 2 |
 Rams |
at |
Bills |
Sunday, September 27, 1970 |
3:00PM |
LA 19, BUF 0 |
| Regular Season: Week 3 |
 Jets |
at |
Bills |
Sunday, October 4, 1970 |
3:00PM |
NYJ 31, BUF 34 |
| Regular Season: Week 4 |
Bills |
at |
 Steelers |
Sunday, October 11, 1970 |
3:00PM |
BUF 10, PIT 23 |
| Regular Season: Week 5 |
 Dolphins |
at |
Bills |
Sunday, October 18, 1970 |
3:00PM |
MIA 33, BUF 14 |
| Regular Season: Week 6 |
Bills |
at |
Jets |
Sunday, October 25, 1970 |
2:00PM |
BUF 10, NYJ 6 |
| Regular Season: Week 7 |
Bills |
at |
 Patriots |
Sunday, November 1, 1970 |
3:00PM |
BUF 45, BOS 10 |
| Regular Season: Week 8 |
 Bengals |
at |
Bills |
Sunday, November 8, 1970 |
3:00PM |
CIN 43, BUF 14 |
| Regular Season: Week 9 |
Bills |
at |
 Colts |
Sunday, November 15, 1970 |
3:00PM |
BUF 17, BAL 17 |
| Regular Season: Week 10 |
Bills |
at |
 Bears |
Sunday, November 22, 1970 |
3:00PM |
BUF 13, CHI 31 |
| Regular Season: Week 11 |
Patriots |
at |
Bills |
Sunday, November 29, 1970 |
3:00PM |
BOS 14, BUF 10 |
| Regular Season: Week 12 |
Bills |
at |
 Giants |
Sunday, December 6, 1970 |
3:00PM |
BUF 6, NYG 20 |
| Regular Season: Week 13 |
Colts |
at |
Bills |
Sunday, December 13, 1970 |
3:00PM |
BAL 20, BUF 14 |
| Regular Season: Week 14 |
Bills |
at |
Dolphins |
Sunday, December 20, 1970 |
3:00PM |
BUF 7, MIA 45 |