| Regular Season: Week 1 |
 Raiders |
at |
 Bills |
Monday, September 16, 1974 |
3:00PM |
OAK 20, BUF 21 |
| Regular Season: Week 2 |
 Dolphins |
at |
Bills |
Sunday, September 22, 1974 |
3:00PM |
MIA 24, BUF 16 |
| Regular Season: Week 3 |
 Jets |
at |
Bills |
Sunday, September 29, 1974 |
3:00PM |
NYJ 12, BUF 16 |
| Regular Season: Week 4 |
Bills |
at |
 Packers |
Sunday, October 6, 1974 |
3:00PM |
BUF 27, GB 7 |
| Regular Season: Week 5 |
Bills |
at |
 Colts |
Sunday, October 13, 1974 |
3:00PM |
BUF 27, BAL 14 |
| Regular Season: Week 6 |
 Patriots |
at |
Bills |
Sunday, October 20, 1974 |
3:00PM |
NE 28, BUF 30 |
| Regular Season: Week 7 |
 Bears |
at |
Bills |
Sunday, October 27, 1974 |
2:00PM |
CHI 6, BUF 16 |
| Regular Season: Week 8 |
Bills |
at |
Patriots |
Sunday, November 3, 1974 |
3:00PM |
BUF 29, NE 28 |
| Regular Season: Week 9 |
 Oilers |
at |
Bills |
Sunday, November 10, 1974 |
3:00PM |
HOU 21, BUF 9 |
| Regular Season: Week 10 |
Bills |
at |
Dolphins |
Sunday, November 17, 1974 |
3:00PM |
BUF 28, MIA 35 |
| Regular Season: Week 11 |
Bills |
at |
 Browns |
Sunday, November 24, 1974 |
3:00PM |
BUF 15, CLE 10 |
| Regular Season: Week 12 |
Colts |
at |
Bills |
Sunday, December 1, 1974 |
3:00PM |
BAL 0, BUF 6 |
| Regular Season: Week 13 |
Bills |
at |
Jets |
Sunday, December 8, 1974 |
3:00PM |
BUF 10, NYJ 20 |
| Regular Season: Week 14 |
Bills |
at |
 Rams |
Sunday, December 15, 1974 |
3:00PM |
BUF 14, LA 19 |
| Divisional Playoffs: Week 15 |
Bills |
at |
 Steelers |
Sunday, December 22, 1974 |
3:00PM |
BUF 14, PIT 32 |