| Regular Season: Week 1 |
 Patriots |
at |
 Bills |
Sunday, September 2, 1984 |
3:00PM |
NE 21, BUF 17 |
| Regular Season: Week 2 |
Bills |
at |
 Cardinals |
Sunday, September 9, 1984 |
3:00PM |
BUF 7, STL 37 |
| Regular Season: Week 3 |
 Dolphins |
at |
Bills |
Monday, September 17, 1984 |
3:00PM |
MIA 21, BUF 17 |
| Regular Season: Week 4 |
 Jets |
at |
Bills |
Sunday, September 23, 1984 |
3:00PM |
NYJ 28, BUF 26 |
| Regular Season: Week 5 |
Bills |
at |
 Colts |
Sunday, September 30, 1984 |
3:00PM |
BUF 17, IND 31 |
| Regular Season: Week 6 |
 Eagles |
at |
Bills |
Sunday, October 7, 1984 |
3:00PM |
PHI 27, BUF 17 |
| Regular Season: Week 7 |
Bills |
at |
 Seahawks |
Sunday, October 14, 1984 |
3:00PM |
BUF 28, SEA 31 |
| Regular Season: Week 8 |
 Broncos |
at |
Bills |
Sunday, October 21, 1984 |
3:00PM |
DEN 37, BUF 7 |
| Regular Season: Week 9 |
Bills |
at |
Dolphins |
Sunday, October 28, 1984 |
2:00PM |
BUF 7, MIA 38 |
| Regular Season: Week 10 |
 Browns |
at |
Bills |
Sunday, November 4, 1984 |
3:00PM |
CLE 13, BUF 10 |
| Regular Season: Week 11 |
Bills |
at |
Patriots |
Sunday, November 11, 1984 |
3:00PM |
BUF 10, NE 38 |
| Regular Season: Week 12 |
 Cowboys |
at |
Bills |
Sunday, November 18, 1984 |
3:00PM |
DAL 3, BUF 14 |
| Regular Season: Week 13 |
Bills |
at |
 Redskins |
Sunday, November 25, 1984 |
3:00PM |
BUF 14, WAS 41 |
| Regular Season: Week 14 |
Colts |
at |
Bills |
Sunday, December 2, 1984 |
3:00PM |
IND 15, BUF 21 |
| Regular Season: Week 15 |
Bills |
at |
Jets |
Saturday, December 8, 1984 |
3:00PM |
BUF 17, NYJ 21 |
| Regular Season: Week 16 |
Bills |
at |
 Bengals |
Sunday, December 16, 1984 |
3:00PM |
BUF 21, CIN 52 |