| Regular Season: Week 1 |
 Bills |
at |
 Patriots |
Sunday, September 10, 2006 |
1:00PM |
BUF 17, NE 19 |
| Regular Season: Week 2 |
Bills |
at |
 Dolphins |
Sunday, September 17, 2006 |
1:00PM |
BUF 16, MIA 6 |
| Regular Season: Week 3 |
 Jets |
at |
Bills |
Sunday, September 24, 2006 |
1:00PM |
NYJ 28, BUF 20 |
| Regular Season: Week 4 |
 Vikings |
at |
Bills |
Sunday, October 1, 2006 |
1:00PM |
MIN 12, BUF 17 |
| Regular Season: Week 5 |
Bills |
at |
 Bears |
Sunday, October 8, 2006 |
1:00PM |
BUF 7, CHI 40 |
| Regular Season: Week 6 |
Bills |
at |
 Lions |
Sunday, October 15, 2006 |
1:00PM |
BUF 17, DET 20 |
| Regular Season: Week 7 |
Patriots |
at |
Bills |
Sunday, October 22, 2006 |
1:00PM |
NE 28, BUF 6 |
| Regular Season: Week 9 |
 Packers |
at |
Bills |
Sunday, November 5, 2006 |
1:00PM |
GB 10, BUF 24 |
| Regular Season: Week 10 |
Bills |
at |
 Colts |
Sunday, November 12, 2006 |
1:00PM |
BUF 16, IND 17 |
| Regular Season: Week 11 |
Bills |
at |
 Texans |
Sunday, November 19, 2006 |
1:00PM |
BUF 24, HOU 21 |
| Regular Season: Week 12 |
 Jaguars |
at |
Bills |
Sunday, November 26, 2006 |
1:00PM |
JAC 24, BUF 27 |
| Regular Season: Week 13 |
 Chargers |
at |
Bills |
Sunday, December 3, 2006 |
1:00PM |
SD 24, BUF 21 |
| Regular Season: Week 14 |
Bills |
at |
Jets |
Sunday, December 10, 2006 |
4:15PM |
BUF 31, NYJ 13 |
| Regular Season: Week 15 |
Dolphins |
at |
Bills |
Sunday, December 17, 2006 |
1:00PM |
MIA 0, BUF 21 |
| Regular Season: Week 16 |
 Titans |
at |
Bills |
Sunday, December 24, 2006 |
1:00PM |
TEN 30, BUF 29 |
| Regular Season: Week 17 |
Bills |
at |
 Ravens |
Sunday, December 31, 2006 |
4:15PM |
BUF 7, BAL 19 |