| Regular Season: Week 1 |
 Broncos |
at |
 Bills |
Sunday, September 9, 2007 |
1:00PM |
DEN 15, BUF 14 |
| Regular Season: Week 2 |
Bills |
at |
 Steelers |
Sunday, September 16, 2007 |
1:00PM |
BUF 3, PIT 26 |
| Regular Season: Week 3 |
Bills |
at |
 Patriots |
Sunday, September 23, 2007 |
1:00PM |
BUF 7, NE 38 |
| Regular Season: Week 4 |
 Jets |
at |
Bills |
Sunday, September 30, 2007 |
1:00PM |
NYJ 14, BUF 17 |
| Regular Season: Week 5 |
 Cowboys |
at |
Bills |
Monday, October 8, 2007 |
8:30PM |
DAL 25, BUF 24 |
| Regular Season: Week 7 |
 Ravens |
at |
Bills |
Sunday, October 21, 2007 |
1:00PM |
BAL 14, BUF 19 |
| Regular Season: Week 8 |
Bills |
at |
Jets |
Sunday, October 28, 2007 |
4:05PM |
BUF 13, NYJ 3 |
| Regular Season: Week 9 |
 Bengals |
at |
Bills |
Sunday, November 4, 2007 |
1:00PM |
CIN 21, BUF 33 |
| Regular Season: Week 10 |
Bills |
at |
 Dolphins |
Sunday, November 11, 2007 |
1:00PM |
BUF 13, MIA 10 |
| Regular Season: Week 11 |
Patriots |
at |
Bills |
Sunday, November 18, 2007 |
8:15PM |
NE 56, BUF 10 |
| Regular Season: Week 12 |
Bills |
at |
 Jaguars |
Sunday, November 25, 2007 |
1:00PM |
BUF 14, JAC 36 |
| Regular Season: Week 13 |
Bills |
at |
 Redskins |
Sunday, December 2, 2007 |
1:00PM |
BUF 17, WAS 16 |
| Regular Season: Week 14 |
Dolphins |
at |
Bills |
Sunday, December 9, 2007 |
1:00PM |
MIA 17, BUF 38 |
| Regular Season: Week 15 |
Bills |
at |
 Browns |
Sunday, December 16, 2007 |
1:00PM |
BUF 0, CLE 8 |
| Regular Season: Week 16 |
 Giants |
at |
Bills |
Sunday, December 23, 2007 |
1:00PM |
NYG 38, BUF 21 |
| Regular Season: Week 17 |
Bills |
at |
 Eagles |
Sunday, December 30, 2007 |
1:00PM |
BUF 9, PHI 17 |