| Regular Season: Week 1 |
 Patriots |
at |
 Bills |
Sunday, September 8, 2013 |
1:00PM |
NE 23, BUF 21 |
| Regular Season: Week 2 |
 Panthers |
at |
Bills |
Sunday, September 15, 2013 |
1:00PM |
CAR 23, BUF 24 |
| Regular Season: Week 3 |
Bills |
at |
 Jets |
Sunday, September 22, 2013 |
4:25PM |
BUF 20, NYJ 27 |
| Regular Season: Week 4 |
 Ravens |
at |
Bills |
Sunday, September 29, 2013 |
1:00PM |
BAL 20, BUF 23 |
| Regular Season: Week 5 |
Bills |
at |
 Browns |
Thursday, October 3, 2013 |
8:25PM |
BUF 24, CLE 37 |
| Regular Season: Week 6 |
 Bengals |
at |
Bills |
Sunday, October 13, 2013 |
1:00PM |
CIN 27, BUF 24 |
| Regular Season: Week 7 |
Bills |
at |
 Dolphins |
Sunday, October 20, 2013 |
1:00PM |
BUF 23, MIA 21 |
| Regular Season: Week 8 |
Bills |
at |
 Saints |
Sunday, October 27, 2013 |
1:00PM |
BUF 17, NO 35 |
| Regular Season: Week 9 |
 Chiefs |
at |
Bills |
Sunday, November 3, 2013 |
1:00PM |
KC 23, BUF 13 |
| Regular Season: Week 10 |
Bills |
at |
 Steelers |
Sunday, November 10, 2013 |
1:00PM |
BUF 10, PIT 23 |
| Regular Season: Week 11 |
Jets |
at |
Bills |
Sunday, November 17, 2013 |
1:00PM |
NYJ 14, BUF 37 |
| Regular Season: Week 13 |
 Falcons |
at |
Bills |
Sunday, December 1, 2013 |
4:05PM |
ATL 34, BUF 31 |
| Regular Season: Week 14 |
Bills |
at |
 Buccaneers |
Sunday, December 8, 2013 |
1:00PM |
BUF 6, TB 27 |
| Regular Season: Week 15 |
Bills |
at |
 Jaguars |
Sunday, December 15, 2013 |
1:00PM |
BUF 27, JAC 20 |
| Regular Season: Week 16 |
Dolphins |
at |
Bills |
Sunday, December 22, 2013 |
1:00PM |
MIA 0, BUF 19 |
| Regular Season: Week 17 |
Bills |
at |
Patriots |
Sunday, December 29, 2013 |
4:25PM |
BUF 20, NE 34 |