| Regular Season: Week 1 |
 Raiders |
at |
 Broncos |
Sunday, September 3, 1978 |
3:00PM |
OAK 6, DEN 14 |
| Regular Season: Week 2 |
Broncos |
at |
 Vikings |
Monday, September 11, 1978 |
3:00PM |
DEN 9, MIN 12 |
| Regular Season: Week 3 |
 Chargers |
at |
Broncos |
Sunday, September 17, 1978 |
3:00PM |
SD 14, DEN 27 |
| Regular Season: Week 4 |
Broncos |
at |
 Chiefs |
Sunday, September 24, 1978 |
3:00PM |
DEN 23, KC 17 |
| Regular Season: Week 5 |
 Seahawks |
at |
Broncos |
Sunday, October 1, 1978 |
3:00PM |
SEA 7, DEN 28 |
| Regular Season: Week 6 |
Broncos |
at |
Chargers |
Sunday, October 8, 1978 |
3:00PM |
DEN 0, SD 23 |
| Regular Season: Week 7 |
 Bears |
at |
Broncos |
Monday, October 16, 1978 |
3:00PM |
CHI 7, DEN 16 |
| Regular Season: Week 8 |
Broncos |
at |
 Colts |
Sunday, October 22, 1978 |
3:00PM |
DEN 6, BAL 7 |
| Regular Season: Week 9 |
Broncos |
at |
Seahawks |
Sunday, October 29, 1978 |
2:00PM |
DEN 20, SEA 17 |
| Regular Season: Week 10 |
 Jets |
at |
Broncos |
Sunday, November 5, 1978 |
3:00PM |
NYJ 31, DEN 28 |
| Regular Season: Week 11 |
Broncos |
at |
 Browns |
Sunday, November 12, 1978 |
3:00PM |
DEN 19, CLE 7 |
| Regular Season: Week 12 |
 Packers |
at |
Broncos |
Sunday, November 19, 1978 |
3:00PM |
GB 3, DEN 16 |
| Regular Season: Week 13 |
Broncos |
at |
 Lions |
Thursday, November 23, 1978 |
3:00PM |
DEN 14, DET 17 |
| Regular Season: Week 14 |
Broncos |
at |
Raiders |
Sunday, December 3, 1978 |
3:00PM |
DEN 21, OAK 6 |
| Regular Season: Week 15 |
Chiefs |
at |
Broncos |
Sunday, December 10, 1978 |
3:00PM |
KC 3, DEN 24 |
| Regular Season: Week 16 |
 Steelers |
at |
Broncos |
Saturday, December 16, 1978 |
3:00PM |
PIT 21, DEN 17 |
| Divisional Playoffs: Week 18 |
Broncos |
at |
Steelers |
Saturday, December 30, 1978 |
3:00PM |
DEN 10, PIT 33 |