| Regular Season: Week 1 |
 Browns |
at |
 Buccaneers |
Sunday, September 12, 2010 |
1:00PM |
CLE 14, TB 17 |
| Regular Season: Week 2 |
 Chiefs |
at |
Browns |
Sunday, September 19, 2010 |
1:00PM |
KC 16, CLE 14 |
| Regular Season: Week 3 |
Browns |
at |
 Ravens |
Sunday, September 26, 2010 |
1:00PM |
CLE 17, BAL 24 |
| Regular Season: Week 4 |
 Bengals |
at |
Browns |
Sunday, October 3, 2010 |
1:00PM |
CIN 20, CLE 23 |
| Regular Season: Week 5 |
 Falcons |
at |
Browns |
Sunday, October 10, 2010 |
1:00PM |
ATL 20, CLE 10 |
| Regular Season: Week 6 |
Browns |
at |
 Steelers |
Sunday, October 17, 2010 |
1:00PM |
CLE 10, PIT 28 |
| Regular Season: Week 7 |
Browns |
at |
 Saints |
Sunday, October 24, 2010 |
1:00PM |
CLE 30, NO 17 |
| Regular Season: Week 9 |
 Patriots |
at |
Browns |
Sunday, November 7, 2010 |
1:00PM |
NE 14, CLE 34 |
| Regular Season: Week 10 |
 Jets |
at |
Browns |
Sunday, November 14, 2010 |
1:00PM |
NYJ 26, CLE 20 |
| Regular Season: Week 11 |
Browns |
at |
 Jaguars |
Sunday, November 21, 2010 |
1:00PM |
CLE 20, JAC 24 |
| Regular Season: Week 12 |
 Panthers |
at |
Browns |
Sunday, November 28, 2010 |
1:00PM |
CAR 23, CLE 24 |
| Regular Season: Week 13 |
Browns |
at |
 Dolphins |
Sunday, December 5, 2010 |
1:00PM |
CLE 13, MIA 10 |
| Regular Season: Week 14 |
Browns |
at |
 Bills |
Sunday, December 12, 2010 |
1:00PM |
CLE 6, BUF 13 |
| Regular Season: Week 15 |
Browns |
at |
Bengals |
Sunday, December 19, 2010 |
1:00PM |
CLE 17, CIN 19 |
| Regular Season: Week 16 |
Ravens |
at |
Browns |
Sunday, December 26, 2010 |
1:00PM |
BAL 20, CLE 10 |
| Regular Season: Week 17 |
Steelers |
at |
Browns |
Sunday, January 2, 2011 |
1:00PM |
PIT 41, CLE 9 |