| Regular Season: Week 1 |
 Browns |
at |
 Buccaneers |
Sunday, September 12, 2010 |
1:00PM |
CLE 14, TB 17 |
| Regular Season: Week 2 |
Buccaneers |
at |
 Panthers |
Sunday, September 19, 2010 |
1:00PM |
TB 20, CAR 7 |
| Regular Season: Week 3 |
 Steelers |
at |
Buccaneers |
Sunday, September 26, 2010 |
1:00PM |
PIT 38, TB 13 |
| Regular Season: Week 5 |
Buccaneers |
at |
 Bengals |
Sunday, October 10, 2010 |
1:00PM |
TB 24, CIN 21 |
| Regular Season: Week 6 |
 Saints |
at |
Buccaneers |
Sunday, October 17, 2010 |
1:00PM |
NO 31, TB 6 |
| Regular Season: Week 7 |
 Rams |
at |
Buccaneers |
Sunday, October 24, 2010 |
1:00PM |
STL 17, TB 18 |
| Regular Season: Week 8 |
Buccaneers |
at |
 Cardinals |
Sunday, October 31, 2010 |
4:15PM |
TB 38, ARI 35 |
| Regular Season: Week 9 |
Buccaneers |
at |
 Falcons |
Sunday, November 7, 2010 |
1:00PM |
TB 21, ATL 27 |
| Regular Season: Week 10 |
Panthers |
at |
Buccaneers |
Sunday, November 14, 2010 |
1:00PM |
CAR 16, TB 31 |
| Regular Season: Week 11 |
Buccaneers |
at |
 49ers |
Sunday, November 21, 2010 |
4:05PM |
TB 21, SF 0 |
| Regular Season: Week 12 |
Buccaneers |
at |
 Ravens |
Sunday, November 28, 2010 |
4:15PM |
TB 10, BAL 17 |
| Regular Season: Week 13 |
Falcons |
at |
Buccaneers |
Sunday, December 5, 2010 |
4:15PM |
ATL 28, TB 24 |
| Regular Season: Week 14 |
Buccaneers |
at |
 Redskins |
Sunday, December 12, 2010 |
1:00PM |
TB 17, WAS 16 |
| Regular Season: Week 15 |
 Lions |
at |
Buccaneers |
Sunday, December 19, 2010 |
1:00PM |
DET 23, TB 20 |
| Regular Season: Week 16 |
 Seahawks |
at |
Buccaneers |
Sunday, December 26, 2010 |
4:15PM |
SEA 15, TB 38 |
| Regular Season: Week 17 |
Buccaneers |
at |
Saints |
Sunday, January 2, 2011 |
1:00PM |
TB 23, NO 13 |