| Regular Season: Week 1 |
 Falcons |
at |
 Cardinals |
Sunday, September 21, 1975 |
3:00PM |
ATL 20, STL 23 |
| Regular Season: Week 2 |
Cardinals |
at |
 Cowboys |
Sunday, September 28, 1975 |
3:00PM |
STL 31, DAL 37 |
| Regular Season: Week 3 |
 Giants |
at |
Cardinals |
Sunday, October 5, 1975 |
3:00PM |
NYG 14, STL 26 |
| Regular Season: Week 4 |
Cardinals |
at |
 Redskins |
Monday, October 13, 1975 |
3:00PM |
STL 17, WAS 27 |
| Regular Season: Week 5 |
 Eagles |
at |
Cardinals |
Sunday, October 19, 1975 |
3:00PM |
PHI 20, STL 31 |
| Regular Season: Week 6 |
Cardinals |
at |
Giants |
Saturday, October 25, 1975 |
3:00PM |
STL 20, NYG 13 |
| Regular Season: Week 7 |
 Patriots |
at |
Cardinals |
Sunday, November 2, 1975 |
3:00PM |
NE 17, STL 24 |
| Regular Season: Week 8 |
Cardinals |
at |
Eagles |
Sunday, November 9, 1975 |
3:00PM |
STL 24, PHI 23 |
| Regular Season: Week 9 |
Redskins |
at |
Cardinals |
Sunday, November 16, 1975 |
3:00PM |
WAS 17, STL 20 |
| Regular Season: Week 10 |
Cardinals |
at |
 Jets |
Sunday, November 23, 1975 |
3:00PM |
STL 37, NYJ 6 |
| Regular Season: Week 11 |
 Bills |
at |
Cardinals |
Thursday, November 27, 1975 |
3:00PM |
BUF 32, STL 14 |
| Regular Season: Week 12 |
Cowboys |
at |
Cardinals |
Sunday, December 7, 1975 |
3:00PM |
DAL 17, STL 31 |
| Regular Season: Week 13 |
Cardinals |
at |
 Bears |
Sunday, December 14, 1975 |
3:00PM |
STL 34, CHI 20 |
| Regular Season: Week 14 |
Cardinals |
at |
 Lions |
Sunday, December 21, 1975 |
3:00PM |
STL 24, DET 13 |
| Divisional Playoffs: Week 15 |
Cardinals |
at |
 Rams |
Saturday, December 27, 1975 |
3:00PM |
STL 23, LA 35 |