| Regular Season: Week 1 |
 Cardinals |
at |
 Browns |
Sunday, September 8, 1985 |
3:00PM |
STL 27, CLE 24 |
| Regular Season: Week 2 |
 Bengals |
at |
Cardinals |
Sunday, September 15, 1985 |
3:00PM |
CIN 27, STL 41 |
| Regular Season: Week 3 |
Cardinals |
at |
 Giants |
Sunday, September 22, 1985 |
3:00PM |
STL 17, NYG 27 |
| Regular Season: Week 4 |
 Packers |
at |
Cardinals |
Sunday, September 29, 1985 |
3:00PM |
GB 28, STL 43 |
| Regular Season: Week 5 |
Cardinals |
at |
 Redskins |
Monday, October 7, 1985 |
3:00PM |
STL 10, WAS 27 |
| Regular Season: Week 6 |
Cardinals |
at |
 Eagles |
Sunday, October 13, 1985 |
3:00PM |
STL 7, PHI 30 |
| Regular Season: Week 7 |
Cardinals |
at |
 Steelers |
Sunday, October 20, 1985 |
3:00PM |
STL 10, PIT 23 |
| Regular Season: Week 8 |
 Oilers |
at |
Cardinals |
Sunday, October 27, 1985 |
2:00PM |
HOU 20, STL 10 |
| Regular Season: Week 9 |
 Cowboys |
at |
Cardinals |
Monday, November 4, 1985 |
3:00PM |
DAL 10, STL 21 |
| Regular Season: Week 10 |
Cardinals |
at |
 Buccaneers |
Sunday, November 10, 1985 |
3:00PM |
STL 0, TB 16 |
| Regular Season: Week 11 |
Eagles |
at |
Cardinals |
Sunday, November 17, 1985 |
3:00PM |
PHI 24, STL 14 |
| Regular Season: Week 12 |
Giants |
at |
Cardinals |
Sunday, November 24, 1985 |
3:00PM |
NYG 34, STL 3 |
| Regular Season: Week 13 |
Cardinals |
at |
Cowboys |
Thursday, November 28, 1985 |
3:00PM |
STL 17, DAL 35 |
| Regular Season: Week 14 |
 Saints |
at |
Cardinals |
Sunday, December 8, 1985 |
3:00PM |
NO 16, STL 28 |
| Regular Season: Week 15 |
Cardinals |
at |
 Rams |
Sunday, December 15, 1985 |
3:00PM |
STL 14, RAM 46 |
| Regular Season: Week 16 |
Redskins |
at |
Cardinals |
Saturday, December 21, 1985 |
3:00PM |
WAS 27, STL 16 |