| Regular Season: Week 1 |
 Dolphins |
at |
 Chargers |
Sunday, September 7, 1986 |
3:00PM |
MIA 28, SD 50 |
| Regular Season: Week 2 |
Chargers |
at |
 Giants |
Sunday, September 14, 1986 |
3:00PM |
SD 7, NYG 20 |
| Regular Season: Week 3 |
 Redskins |
at |
Chargers |
Sunday, September 21, 1986 |
3:00PM |
WAS 30, SD 27 |
| Regular Season: Week 4 |
Chargers |
at |
 Raiders |
Sunday, September 28, 1986 |
3:00PM |
SD 13, RAI 17 |
| Regular Season: Week 5 |
Chargers |
at |
 Seahawks |
Monday, October 6, 1986 |
3:00PM |
SD 7, SEA 33 |
| Regular Season: Week 6 |
 Broncos |
at |
Chargers |
Sunday, October 12, 1986 |
3:00PM |
DEN 31, SD 14 |
| Regular Season: Week 7 |
Chargers |
at |
 Chiefs |
Sunday, October 19, 1986 |
3:00PM |
SD 41, KC 42 |
| Regular Season: Week 8 |
Chargers |
at |
 Eagles |
Sunday, October 26, 1986 |
2:00PM |
SD 7, PHI 23 |
| Regular Season: Week 9 |
Chiefs |
at |
Chargers |
Sunday, November 2, 1986 |
3:00PM |
KC 24, SD 23 |
| Regular Season: Week 10 |
Chargers |
at |
Broncos |
Sunday, November 9, 1986 |
3:00PM |
SD 9, DEN 3 |
| Regular Season: Week 11 |
 Cowboys |
at |
Chargers |
Sunday, November 16, 1986 |
3:00PM |
DAL 24, SD 21 |
| Regular Season: Week 12 |
Raiders |
at |
Chargers |
Thursday, November 20, 1986 |
3:00PM |
RAI 37, SD 31 |
| Regular Season: Week 13 |
Chargers |
at |
 Colts |
Sunday, November 30, 1986 |
3:00PM |
SD 17, IND 3 |
| Regular Season: Week 14 |
 Oilers |
at |
Chargers |
Sunday, December 7, 1986 |
3:00PM |
HOU 0, SD 27 |
| Regular Season: Week 15 |
Seahawks |
at |
Chargers |
Sunday, December 14, 1986 |
3:00PM |
SEA 34, SD 24 |
| Regular Season: Week 16 |
Chargers |
at |
 Browns |
Sunday, December 21, 1986 |
3:00PM |
SD 17, CLE 47 |