| Regular Season: Week 1 |
 Chargers |
at |
 Raiders |
Sunday, September 10, 1989 |
3:00PM |
SD 14, RAI 40 |
| Regular Season: Week 2 |
 Oilers |
at |
Chargers |
Sunday, September 17, 1989 |
3:00PM |
HOU 34, SD 27 |
| Regular Season: Week 3 |
 Chiefs |
at |
Chargers |
Sunday, September 24, 1989 |
3:00PM |
KC 6, SD 21 |
| Regular Season: Week 4 |
Chargers |
at |
 Cardinals |
Sunday, October 1, 1989 |
3:00PM |
SD 24, PHO 13 |
| Regular Season: Week 5 |
Chargers |
at |
 Broncos |
Sunday, October 8, 1989 |
3:00PM |
SD 10, DEN 16 |
| Regular Season: Week 6 |
 Seahawks |
at |
Chargers |
Sunday, October 15, 1989 |
3:00PM |
SEA 17, SD 16 |
| Regular Season: Week 7 |
 Giants |
at |
Chargers |
Sunday, October 22, 1989 |
3:00PM |
NYG 20, SD 13 |
| Regular Season: Week 8 |
Chargers |
at |
Seahawks |
Sunday, October 29, 1989 |
2:00PM |
SD 7, SEA 10 |
| Regular Season: Week 9 |
 Eagles |
at |
Chargers |
Sunday, November 5, 1989 |
3:00PM |
PHI 17, SD 20 |
| Regular Season: Week 10 |
Raiders |
at |
Chargers |
Sunday, November 12, 1989 |
3:00PM |
RAI 12, SD 14 |
| Regular Season: Week 11 |
Chargers |
at |
 Steelers |
Sunday, November 19, 1989 |
3:00PM |
SD 17, PIT 20 |
| Regular Season: Week 12 |
Chargers |
at |
 Colts |
Sunday, November 26, 1989 |
3:00PM |
SD 6, IND 10 |
| Regular Season: Week 13 |
 Jets |
at |
Chargers |
Sunday, December 3, 1989 |
3:00PM |
NYJ 20, SD 17 |
| Regular Season: Week 14 |
Chargers |
at |
 Redskins |
Sunday, December 10, 1989 |
3:00PM |
SD 21, WAS 26 |
| Regular Season: Week 15 |
Chargers |
at |
Chiefs |
Sunday, December 17, 1989 |
3:00PM |
SD 20, KC 13 |
| Regular Season: Week 16 |
Broncos |
at |
Chargers |
Sunday, December 24, 1989 |
3:00PM |
DEN 16, SD 19 |