| Regular Season: Week 1 |
 Bills |
at |
 Chargers |
Sunday, September 6, 1998 |
3:00PM |
BUF 14, SD 16 |
| Regular Season: Week 2 |
Chargers |
at |
 Oilers |
Sunday, September 13, 1998 |
3:00PM |
SD 13, TEN 7 |
| Regular Season: Week 3 |
Chargers |
at |
 Chiefs |
Sunday, September 20, 1998 |
3:00PM |
SD 7, KC 23 |
| Regular Season: Week 4 |
 Giants |
at |
Chargers |
Sunday, September 27, 1998 |
3:00PM |
NYG 34, SD 16 |
| Regular Season: Week 5 |
Chargers |
at |
 Colts |
Sunday, October 4, 1998 |
3:00PM |
SD 12, IND 17 |
| Regular Season: Week 6 |
Chargers |
at |
 Raiders |
Sunday, October 11, 1998 |
3:00PM |
SD 6, OAK 7 |
| Regular Season: Week 7 |
 Eagles |
at |
Chargers |
Sunday, October 18, 1998 |
3:00PM |
PHI 10, SD 13 |
| Regular Season: Week 8 |
 Seahawks |
at |
Chargers |
Sunday, October 25, 1998 |
2:00PM |
SEA 27, SD 20 |
| Regular Season: Week 10 |
Chargers |
at |
 Broncos |
Sunday, November 8, 1998 |
3:00PM |
SD 10, DEN 27 |
| Regular Season: Week 11 |
 Ravens |
at |
Chargers |
Sunday, November 15, 1998 |
3:00PM |
BAL 13, SD 14 |
| Regular Season: Week 12 |
Chiefs |
at |
Chargers |
Sunday, November 22, 1998 |
3:00PM |
KC 37, SD 38 |
| Regular Season: Week 13 |
Broncos |
at |
Chargers |
Sunday, November 29, 1998 |
3:00PM |
DEN 31, SD 16 |
| Regular Season: Week 14 |
Chargers |
at |
 Redskins |
Sunday, December 6, 1998 |
3:00PM |
SD 20, WAS 24 |
| Regular Season: Week 15 |
Chargers |
at |
Seahawks |
Sunday, December 13, 1998 |
3:00PM |
SD 17, SEA 38 |
| Regular Season: Week 16 |
Raiders |
at |
Chargers |
Sunday, December 20, 1998 |
3:00PM |
OAK 17, SD 10 |
| Regular Season: Week 17 |
Chargers |
at |
 Cardinals |
Sunday, December 27, 1998 |
3:00PM |
SD 13, ARI 16 |