| Regular Season: Week 1 |
 Vikings |
at |
 Chargers |
Sunday, September 11, 2011 |
4:15PM |
MIN 17, SD 24 |
| Regular Season: Week 2 |
Chargers |
at |
 Patriots |
Sunday, September 18, 2011 |
4:15PM |
SD 21, NE 35 |
| Regular Season: Week 3 |
 Chiefs |
at |
Chargers |
Sunday, September 25, 2011 |
4:05PM |
KC 17, SD 20 |
| Regular Season: Week 4 |
 Dolphins |
at |
Chargers |
Sunday, October 2, 2011 |
4:15PM |
MIA 16, SD 26 |
| Regular Season: Week 5 |
Chargers |
at |
 Broncos |
Sunday, October 9, 2011 |
4:15PM |
SD 29, DEN 24 |
| Regular Season: Week 7 |
Chargers |
at |
 Jets |
Sunday, October 23, 2011 |
1:00PM |
SD 21, NYJ 27 |
| Regular Season: Week 8 |
Chargers |
at |
Chiefs |
Monday, October 31, 2011 |
8:30PM |
SD 20, KC 23 |
| Regular Season: Week 9 |
 Packers |
at |
Chargers |
Sunday, November 6, 2011 |
4:15PM |
GB 45, SD 38 |
| Regular Season: Week 10 |
 Raiders |
at |
Chargers |
Thursday, November 10, 2011 |
8:20PM |
OAK 24, SD 17 |
| Regular Season: Week 11 |
Chargers |
at |
 Bears |
Sunday, November 20, 2011 |
4:15PM |
SD 20, CHI 31 |
| Regular Season: Week 12 |
Broncos |
at |
Chargers |
Sunday, November 27, 2011 |
4:15PM |
DEN 16, SD 13 |
| Regular Season: Week 13 |
Chargers |
at |
 Jaguars |
Monday, December 5, 2011 |
8:30PM |
SD 38, JAC 14 |
| Regular Season: Week 14 |
 Bills |
at |
Chargers |
Sunday, December 11, 2011 |
4:15PM |
BUF 10, SD 37 |
| Regular Season: Week 15 |
 Ravens |
at |
Chargers |
Sunday, December 18, 2011 |
8:20PM |
BAL 14, SD 34 |
| Regular Season: Week 16 |
Chargers |
at |
 Lions |
Saturday, December 24, 2011 |
4:05PM |
SD 10, DET 38 |
| Regular Season: Week 17 |
Chargers |
at |
Raiders |
Sunday, January 1, 2012 |
4:15PM |
SD 38, OAK 26 |