| Regular Season: Week 1 |
 Colts |
at |
 Ravens |
Sunday, September 11, 2005 |
8:30PM |
IND 24, BAL 7 |
| Regular Season: Week 2 |
 Jaguars |
at |
Colts |
Sunday, September 18, 2005 |
1:00PM |
JAC 3, IND 10 |
| Regular Season: Week 3 |
 Browns |
at |
Colts |
Sunday, September 25, 2005 |
1:00PM |
CLE 6, IND 13 |
| Regular Season: Week 4 |
Colts |
at |
 Titans |
Sunday, October 2, 2005 |
1:00PM |
IND 31, TEN 10 |
| Regular Season: Week 5 |
Colts |
at |
 49ers |
Sunday, October 9, 2005 |
4:05PM |
IND 28, SF 3 |
| Regular Season: Week 6 |
 Rams |
at |
Colts |
Monday, October 17, 2005 |
9:00PM |
STL 28, IND 45 |
| Regular Season: Week 7 |
Colts |
at |
 Texans |
Sunday, October 23, 2005 |
1:00PM |
IND 38, HOU 20 |
| Regular Season: Week 9 |
Colts |
at |
 Patriots |
Monday, November 7, 2005 |
9:00PM |
IND 40, NE 21 |
| Regular Season: Week 10 |
Texans |
at |
Colts |
Sunday, November 13, 2005 |
1:00PM |
HOU 17, IND 31 |
| Regular Season: Week 11 |
Colts |
at |
 Bengals |
Sunday, November 20, 2005 |
4:15PM |
IND 45, CIN 37 |
| Regular Season: Week 12 |
 Steelers |
at |
Colts |
Monday, November 28, 2005 |
9:00PM |
PIT 7, IND 26 |
| Regular Season: Week 13 |
Titans |
at |
Colts |
Sunday, December 4, 2005 |
1:00PM |
TEN 3, IND 35 |
| Regular Season: Week 14 |
Colts |
at |
Jaguars |
Sunday, December 11, 2005 |
1:00PM |
IND 26, JAC 18 |
| Regular Season: Week 15 |
 Chargers |
at |
Colts |
Sunday, December 18, 2005 |
1:00PM |
SD 26, IND 17 |
| Regular Season: Week 16 |
Colts |
at |
 Seahawks |
Saturday, December 24, 2005 |
4:15PM |
IND 13, SEA 28 |
| Regular Season: Week 17 |
 Cardinals |
at |
Colts |
Sunday, January 1, 2006 |
1:00PM |
ARI 13, IND 17 |
| Divisional Playoffs: Week 19 |
Steelers |
at |
Colts |
Sunday, January 15, 2006 |
1:00PM |
PIT 21, IND 18 |