| Regular Season: Week 1 |
 Eagles |
at |
 Buccaneers |
Sunday, September 4, 1988 |
3:00PM |
PHI 41, TB 14 |
| Regular Season: Week 2 |
 Bengals |
at |
Eagles |
Sunday, September 11, 1988 |
3:00PM |
CIN 28, PHI 24 |
| Regular Season: Week 3 |
Eagles |
at |
 Redskins |
Sunday, September 18, 1988 |
3:00PM |
PHI 10, WAS 17 |
| Regular Season: Week 4 |
Eagles |
at |
 Vikings |
Sunday, September 25, 1988 |
3:00PM |
PHI 21, MIN 23 |
| Regular Season: Week 5 |
 Oilers |
at |
Eagles |
Sunday, October 2, 1988 |
3:00PM |
HOU 23, PHI 32 |
| Regular Season: Week 6 |
 Giants |
at |
Eagles |
Monday, October 10, 1988 |
3:00PM |
NYG 13, PHI 24 |
| Regular Season: Week 7 |
Eagles |
at |
 Browns |
Sunday, October 16, 1988 |
3:00PM |
PHI 3, CLE 19 |
| Regular Season: Week 8 |
 Cowboys |
at |
Eagles |
Sunday, October 23, 1988 |
3:00PM |
DAL 23, PHI 24 |
| Regular Season: Week 9 |
 Falcons |
at |
Eagles |
Sunday, October 30, 1988 |
2:00PM |
ATL 27, PHI 24 |
| Regular Season: Week 10 |
 Rams |
at |
Eagles |
Sunday, November 6, 1988 |
3:00PM |
RAM 24, PHI 30 |
| Regular Season: Week 11 |
Eagles |
at |
 Steelers |
Sunday, November 13, 1988 |
3:00PM |
PHI 27, PIT 26 |
| Regular Season: Week 12 |
Eagles |
at |
Giants |
Sunday, November 20, 1988 |
3:00PM |
PHI 23, NYG 17 |
| Regular Season: Week 13 |
 Cardinals |
at |
Eagles |
Sunday, November 27, 1988 |
3:00PM |
PHO 21, PHI 31 |
| Regular Season: Week 14 |
Redskins |
at |
Eagles |
Sunday, December 4, 1988 |
3:00PM |
WAS 20, PHI 19 |
| Regular Season: Week 15 |
Eagles |
at |
Cardinals |
Saturday, December 10, 1988 |
3:00PM |
PHI 23, PHO 17 |
| Regular Season: Week 16 |
Eagles |
at |
Cowboys |
Sunday, December 18, 1988 |
3:00PM |
PHI 23, DAL 7 |
| Divisional Playoffs: Week 18 |
Eagles |
at |
 Bears |
Saturday, December 31, 1988 |
3:00PM |
PHI 12, CHI 20 |