| Regular Season: Week 1 |
 Eagles |
at |
 Falcons |
Sunday, September 12, 2021 |
1:00PM |
PHI 32, ATL 6 |
| Regular Season: Week 2 |
 49ers |
at |
Eagles |
Sunday, September 19, 2021 |
1:00PM |
SF 17, PHI 11 |
| Regular Season: Week 3 |
Eagles |
at |
 Cowboys |
Monday, September 27, 2021 |
8:15PM |
PHI 21, DAL 41 |
| Regular Season: Week 4 |
 Chiefs |
at |
Eagles |
Sunday, October 3, 2021 |
1:00PM |
KC 42, PHI 30 |
| Regular Season: Week 5 |
Eagles |
at |
 Panthers |
Sunday, October 10, 2021 |
1:00PM |
PHI 21, CAR 18 |
| Regular Season: Week 6 |
 Buccaneers |
at |
Eagles |
Thursday, October 14, 2021 |
8:20PM |
TB 28, PHI 22 |
| Regular Season: Week 7 |
Eagles |
at |
 Raiders |
Sunday, October 24, 2021 |
4:05PM |
PHI 22, LV 33 |
| Regular Season: Week 8 |
Eagles |
at |
 Lions |
Sunday, October 31, 2021 |
1:00PM |
PHI 44, DET 6 |
| Regular Season: Week 9 |
 Chargers |
at |
Eagles |
Sunday, November 7, 2021 |
4:05PM |
LAC 27, PHI 24 |
| Regular Season: Week 10 |
Eagles |
at |
 Broncos |
Sunday, November 14, 2021 |
4:25PM |
PHI 30, DEN 13 |
| Regular Season: Week 11 |
 Saints |
at |
Eagles |
Sunday, November 21, 2021 |
1:00PM |
NO 29, PHI 40 |
| Regular Season: Week 12 |
Eagles |
at |
 Giants |
Sunday, November 28, 2021 |
1:00PM |
PHI 7, NYG 13 |
| Regular Season: Week 13 |
Eagles |
at |
 Jets |
Sunday, December 5, 2021 |
1:00PM |
PHI 33, NYJ 18 |
| Regular Season: Week 15 |
 Washington |
at |
Eagles |
Sunday, December 19, 2021 |
TBD |
WSH 17, PHI 27 |
| Regular Season: Week 16 |
Giants |
at |
Eagles |
Sunday, December 26, 2021 |
1:00PM |
NYG 10, PHI 34 |
| Regular Season: Week 17 |
Eagles |
at |
Washington |
Sunday, January 2, 2022 |
1:00PM |
PHI 20, WSH 16 |
| Regular Season: Week 18 |
Cowboys |
at |
Eagles |
Sunday, January 9, 2022 |
1:00PM |
DAL 51, PHI 26 |