| Regular Season: Week 1 |
 Vikings |
at |
 Lions |
Monday, September 20, 1971 |
3:00PM |
MIN 16, DET 13 |
| Regular Season: Week 2 |
Lions |
at |
 Patriots |
Sunday, September 26, 1971 |
3:00PM |
DET 34, NE 7 |
| Regular Season: Week 3 |
 Falcons |
at |
Lions |
Sunday, October 3, 1971 |
3:00PM |
ATL 38, DET 41 |
| Regular Season: Week 4 |
 Packers |
at |
Lions |
Sunday, October 10, 1971 |
3:00PM |
GB 28, DET 31 |
| Regular Season: Week 5 |
Lions |
at |
 Oilers |
Sunday, October 17, 1971 |
3:00PM |
DET 31, HOU 7 |
| Regular Season: Week 6 |
 Bears |
at |
Lions |
Sunday, October 24, 1971 |
3:00PM |
CHI 28, DET 23 |
| Regular Season: Week 7 |
Lions |
at |
Packers |
Monday, November 1, 1971 |
3:00PM |
DET 14, GB 14 |
| Regular Season: Week 8 |
Lions |
at |
 Broncos |
Sunday, November 7, 1971 |
3:00PM |
DET 24, DEN 20 |
| Regular Season: Week 9 |
 Rams |
at |
Lions |
Sunday, November 14, 1971 |
3:00PM |
LA 21, DET 13 |
| Regular Season: Week 10 |
Lions |
at |
Bears |
Sunday, November 21, 1971 |
3:00PM |
DET 28, CHI 3 |
| Regular Season: Week 11 |
 Chiefs |
at |
Lions |
Thursday, November 25, 1971 |
3:00PM |
KC 21, DET 32 |
| Regular Season: Week 12 |
 Eagles |
at |
Lions |
Sunday, December 5, 1971 |
3:00PM |
PHI 23, DET 20 |
| Regular Season: Week 13 |
Lions |
at |
Vikings |
Saturday, December 11, 1971 |
3:00PM |
DET 10, MIN 29 |
| Regular Season: Week 14 |
Lions |
at |
 49ers |
Sunday, December 19, 1971 |
3:00PM |
DET 27, SF 31 |