| Regular Season: Week 1 |
 Lions |
at |
 Steelers |
Sunday, September 16, 1973 |
3:00PM |
DET 10, PIT 24 |
| Regular Season: Week 2 |
Lions |
at |
 Packers |
Sunday, September 23, 1973 |
3:00PM |
DET 13, GB 13 |
| Regular Season: Week 3 |
 Falcons |
at |
Lions |
Monday, October 1, 1973 |
3:00PM |
ATL 6, DET 31 |
| Regular Season: Week 4 |
 Vikings |
at |
Lions |
Sunday, October 7, 1973 |
3:00PM |
MIN 23, DET 9 |
| Regular Season: Week 5 |
Lions |
at |
 Saints |
Sunday, October 14, 1973 |
3:00PM |
DET 13, NO 20 |
| Regular Season: Week 6 |
 Colts |
at |
Lions |
Sunday, October 21, 1973 |
3:00PM |
BAL 29, DET 27 |
| Regular Season: Week 7 |
Packers |
at |
Lions |
Sunday, October 28, 1973 |
2:00PM |
GB 0, DET 34 |
| Regular Season: Week 8 |
 49ers |
at |
Lions |
Sunday, November 4, 1973 |
3:00PM |
SF 20, DET 30 |
| Regular Season: Week 9 |
Lions |
at |
Vikings |
Sunday, November 11, 1973 |
3:00PM |
DET 7, MIN 28 |
| Regular Season: Week 10 |
Lions |
at |
 Bears |
Sunday, November 18, 1973 |
3:00PM |
DET 30, CHI 7 |
| Regular Season: Week 11 |
 Redskins |
at |
Lions |
Thursday, November 22, 1973 |
3:00PM |
WAS 20, DET 0 |
| Regular Season: Week 12 |
Lions |
at |
 Cardinals |
Sunday, December 2, 1973 |
3:00PM |
DET 20, STL 16 |
| Regular Season: Week 13 |
Bears |
at |
Lions |
Sunday, December 9, 1973 |
3:00PM |
CHI 7, DET 40 |
| Regular Season: Week 14 |
Lions |
at |
 Dolphins |
Saturday, December 15, 1973 |
3:00PM |
DET 7, MIA 34 |