| Regular Season: Week 1 |
 Lions |
at |
 Vikings |
Sunday, September 7, 1986 |
3:00PM |
DET 13, MIN 10 |
| Regular Season: Week 2 |
 Cowboys |
at |
Lions |
Sunday, September 14, 1986 |
3:00PM |
DAL 31, DET 7 |
| Regular Season: Week 3 |
 Buccaneers |
at |
Lions |
Sunday, September 21, 1986 |
3:00PM |
TB 24, DET 20 |
| Regular Season: Week 4 |
Lions |
at |
 Browns |
Sunday, September 28, 1986 |
3:00PM |
DET 21, CLE 24 |
| Regular Season: Week 5 |
 Oilers |
at |
Lions |
Sunday, October 5, 1986 |
3:00PM |
HOU 13, DET 24 |
| Regular Season: Week 6 |
Lions |
at |
 Packers |
Sunday, October 12, 1986 |
3:00PM |
DET 21, GB 14 |
| Regular Season: Week 7 |
Lions |
at |
 Rams |
Sunday, October 19, 1986 |
3:00PM |
DET 10, RAM 14 |
| Regular Season: Week 8 |
Lions |
at |
 Bears |
Sunday, October 26, 1986 |
2:00PM |
DET 7, CHI 13 |
| Regular Season: Week 9 |
 Bengals |
at |
Lions |
Sunday, November 2, 1986 |
3:00PM |
CIN 24, DET 17 |
| Regular Season: Week 10 |
Vikings |
at |
Lions |
Sunday, November 9, 1986 |
3:00PM |
MIN 24, DET 10 |
| Regular Season: Week 11 |
Lions |
at |
 Eagles |
Sunday, November 16, 1986 |
3:00PM |
DET 13, PHI 11 |
| Regular Season: Week 12 |
Lions |
at |
Buccaneers |
Sunday, November 23, 1986 |
3:00PM |
DET 38, TB 17 |
| Regular Season: Week 13 |
Packers |
at |
Lions |
Thursday, November 27, 1986 |
3:00PM |
GB 44, DET 40 |
| Regular Season: Week 14 |
Lions |
at |
 Steelers |
Sunday, December 7, 1986 |
3:00PM |
DET 17, PIT 27 |
| Regular Season: Week 15 |
Bears |
at |
Lions |
Monday, December 15, 1986 |
3:00PM |
CHI 16, DET 13 |
| Regular Season: Week 16 |
 Falcons |
at |
Lions |
Sunday, December 21, 1986 |
3:00PM |
ATL 20, DET 6 |