| Regular Season: Week 1 |
 Cardinals |
at |
 Lions |
Sunday, September 10, 1989 |
3:00PM |
PHO 16, DET 13 |
| Regular Season: Week 2 |
Lions |
at |
 Giants |
Sunday, September 17, 1989 |
3:00PM |
DET 14, NYG 24 |
| Regular Season: Week 3 |
 Bears |
at |
Lions |
Sunday, September 24, 1989 |
3:00PM |
CHI 47, DET 27 |
| Regular Season: Week 4 |
 Steelers |
at |
Lions |
Sunday, October 1, 1989 |
3:00PM |
PIT 23, DET 3 |
| Regular Season: Week 5 |
Lions |
at |
 Vikings |
Sunday, October 8, 1989 |
3:00PM |
DET 17, MIN 24 |
| Regular Season: Week 6 |
Lions |
at |
 Buccaneers |
Sunday, October 15, 1989 |
3:00PM |
DET 17, TB 16 |
| Regular Season: Week 7 |
Vikings |
at |
Lions |
Sunday, October 22, 1989 |
3:00PM |
MIN 20, DET 7 |
| Regular Season: Week 8 |
Lions |
at |
 Packers |
Sunday, October 29, 1989 |
2:00PM |
DET 20, GB 23 |
| Regular Season: Week 9 |
Lions |
at |
 Oilers |
Sunday, November 5, 1989 |
3:00PM |
DET 31, HOU 35 |
| Regular Season: Week 10 |
Packers |
at |
Lions |
Sunday, November 12, 1989 |
3:00PM |
GB 22, DET 31 |
| Regular Season: Week 11 |
Lions |
at |
 Bengals |
Sunday, November 19, 1989 |
3:00PM |
DET 7, CIN 42 |
| Regular Season: Week 12 |
 Browns |
at |
Lions |
Thursday, November 23, 1989 |
3:00PM |
CLE 10, DET 13 |
| Regular Season: Week 13 |
 Saints |
at |
Lions |
Sunday, December 3, 1989 |
3:00PM |
NO 14, DET 21 |
| Regular Season: Week 14 |
Lions |
at |
Bears |
Sunday, December 10, 1989 |
3:00PM |
DET 27, CHI 17 |
| Regular Season: Week 15 |
Buccaneers |
at |
Lions |
Sunday, December 17, 1989 |
3:00PM |
TB 7, DET 33 |
| Regular Season: Week 16 |
Lions |
at |
 Falcons |
Sunday, December 24, 1989 |
3:00PM |
DET 31, ATL 24 |