| Regular Season: Week 1 |
 Lions |
at |
 Redskins |
Sunday, September 1, 1991 |
3:00PM |
DET 0, WAS 45 |
| Regular Season: Week 2 |
 Packers |
at |
Lions |
Sunday, September 8, 1991 |
3:00PM |
GB 14, DET 23 |
| Regular Season: Week 3 |
 Dolphins |
at |
Lions |
Sunday, September 15, 1991 |
3:00PM |
MIA 13, DET 17 |
| Regular Season: Week 4 |
Lions |
at |
 Colts |
Sunday, September 22, 1991 |
3:00PM |
DET 33, IND 24 |
| Regular Season: Week 5 |
 Buccaneers |
at |
Lions |
Sunday, September 29, 1991 |
3:00PM |
TB 3, DET 31 |
| Regular Season: Week 6 |
 Vikings |
at |
Lions |
Sunday, October 6, 1991 |
3:00PM |
MIN 20, DET 24 |
| Regular Season: Week 8 |
Lions |
at |
 49ers |
Sunday, October 20, 1991 |
3:00PM |
DET 3, SF 35 |
| Regular Season: Week 9 |
 Cowboys |
at |
Lions |
Sunday, October 27, 1991 |
2:00PM |
DAL 10, DET 34 |
| Regular Season: Week 10 |
Lions |
at |
 Bears |
Sunday, November 3, 1991 |
3:00PM |
DET 10, CHI 20 |
| Regular Season: Week 11 |
Lions |
at |
Buccaneers |
Sunday, November 10, 1991 |
3:00PM |
DET 21, TB 30 |
| Regular Season: Week 12 |
 Rams |
at |
Lions |
Sunday, November 17, 1991 |
3:00PM |
RAM 10, DET 21 |
| Regular Season: Week 13 |
Lions |
at |
Vikings |
Sunday, November 24, 1991 |
3:00PM |
DET 34, MIN 14 |
| Regular Season: Week 14 |
Bears |
at |
Lions |
Thursday, November 28, 1991 |
3:00PM |
CHI 6, DET 16 |
| Regular Season: Week 15 |
 Jets |
at |
Lions |
Sunday, December 8, 1991 |
3:00PM |
NYJ 20, DET 34 |
| Regular Season: Week 16 |
Lions |
at |
Packers |
Sunday, December 15, 1991 |
3:00PM |
DET 21, GB 17 |
| Regular Season: Week 17 |
Lions |
at |
 Bills |
Sunday, December 22, 1991 |
3:00PM |
DET 17, BUF 14 |
| Divisional Playoffs: Week 19 |
Cowboys |
at |
Lions |
Sunday, January 5, 1992 |
3:00PM |
DAL 6, DET 38 |
| Conference Championship: Week 20 |
Lions |
at |
Redskins |
Sunday, January 12, 1992 |
3:00PM |
DET 10, WAS 41 |