| Regular Season: Week 1 |
 Seahawks |
at |
 Lions |
Sunday, September 10, 2006 |
1:00PM |
SEA 9, DET 6 |
| Regular Season: Week 2 |
Lions |
at |
 Bears |
Sunday, September 17, 2006 |
1:00PM |
DET 7, CHI 34 |
| Regular Season: Week 3 |
 Packers |
at |
Lions |
Sunday, September 24, 2006 |
1:00PM |
GB 31, DET 24 |
| Regular Season: Week 4 |
Lions |
at |
 Rams |
Sunday, October 1, 2006 |
4:05PM |
DET 34, STL 41 |
| Regular Season: Week 5 |
Lions |
at |
 Vikings |
Sunday, October 8, 2006 |
1:00PM |
DET 17, MIN 26 |
| Regular Season: Week 6 |
 Bills |
at |
Lions |
Sunday, October 15, 2006 |
1:00PM |
BUF 17, DET 20 |
| Regular Season: Week 7 |
Lions |
at |
 Jets |
Sunday, October 22, 2006 |
1:00PM |
DET 24, NYJ 31 |
| Regular Season: Week 9 |
 Falcons |
at |
Lions |
Sunday, November 5, 2006 |
1:00PM |
ATL 14, DET 30 |
| Regular Season: Week 10 |
 49ers |
at |
Lions |
Sunday, November 12, 2006 |
1:00PM |
SF 19, DET 13 |
| Regular Season: Week 11 |
Lions |
at |
 Cardinals |
Sunday, November 19, 2006 |
4:05PM |
DET 10, ARI 17 |
| Regular Season: Week 12 |
 Dolphins |
at |
Lions |
Thursday, November 23, 2006 |
12:30PM |
MIA 27, DET 10 |
| Regular Season: Week 13 |
Lions |
at |
 Patriots |
Sunday, December 3, 2006 |
1:00PM |
DET 21, NE 28 |
| Regular Season: Week 14 |
Vikings |
at |
Lions |
Sunday, December 10, 2006 |
1:00PM |
MIN 30, DET 20 |
| Regular Season: Week 15 |
Lions |
at |
Packers |
Sunday, December 17, 2006 |
1:00PM |
DET 9, GB 17 |
| Regular Season: Week 16 |
Bears |
at |
Lions |
Sunday, December 24, 2006 |
1:00PM |
CHI 26, DET 21 |
| Regular Season: Week 17 |
Lions |
at |
 Cowboys |
Sunday, December 31, 2006 |
1:00PM |
DET 39, DAL 31 |