| Regular Season: Week 1 |
 Panthers |
at |
 Broncos |
Thursday, September 8, 2016 |
8:30PM |
CAR 20, DEN 21 |
| Regular Season: Week 2 |
 49ers |
at |
Panthers |
Sunday, September 18, 2016 |
1:00PM |
SF 27, CAR 46 |
| Regular Season: Week 3 |
 Vikings |
at |
Panthers |
Sunday, September 25, 2016 |
1:00PM |
MIN 22, CAR 10 |
| Regular Season: Week 4 |
Panthers |
at |
 Falcons |
Sunday, October 2, 2016 |
1:00PM |
CAR 33, ATL 48 |
| Regular Season: Week 5 |
 Buccaneers |
at |
Panthers |
Monday, October 10, 2016 |
8:30PM |
TB 17, CAR 14 |
| Regular Season: Week 6 |
Panthers |
at |
 Saints |
Sunday, October 16, 2016 |
1:00PM |
CAR 38, NO 41 |
| Regular Season: Week 8 |
 Cardinals |
at |
Panthers |
Sunday, October 30, 2016 |
1:00PM |
ARI 20, CAR 30 |
| Regular Season: Week 9 |
Panthers |
at |
 Rams |
Sunday, November 6, 2016 |
4:05PM |
CAR 13, LA 10 |
| Regular Season: Week 10 |
 Chiefs |
at |
Panthers |
Sunday, November 13, 2016 |
1:00PM |
KC 20, CAR 17 |
| Regular Season: Week 11 |
Saints |
at |
Panthers |
Thursday, November 17, 2016 |
8:25PM |
NO 20, CAR 23 |
| Regular Season: Week 12 |
Panthers |
at |
 Raiders |
Sunday, November 27, 2016 |
4:25PM |
CAR 32, OAK 35 |
| Regular Season: Week 13 |
Panthers |
at |
 Seahawks |
Sunday, December 4, 2016 |
8:30PM |
CAR 7, SEA 40 |
| Regular Season: Week 14 |
 Chargers |
at |
Panthers |
Sunday, December 11, 2016 |
1:00PM |
SD 16, CAR 28 |
| Regular Season: Week 15 |
Panthers |
at |
 Redskins |
Monday, December 19, 2016 |
8:30PM |
CAR 26, WAS 15 |
| Regular Season: Week 16 |
Falcons |
at |
Panthers |
Saturday, December 24, 2016 |
1:00PM |
ATL 33, CAR 16 |
| Regular Season: Week 17 |
Panthers |
at |
Buccaneers |
Sunday, January 1, 2017 |
1:00PM |
CAR 16, TB 17 |