| Regular Season: Week 1 |
 Jets |
at |
 Panthers |
Sunday, September 12, 2021 |
1:00PM |
NYJ 14, CAR 19 |
| Regular Season: Week 2 |
 Saints |
at |
Panthers |
Sunday, September 19, 2021 |
1:00PM |
NO 7, CAR 26 |
| Regular Season: Week 3 |
Panthers |
at |
 Texans |
Thursday, September 23, 2021 |
8:20PM |
CAR 24, HOU 9 |
| Regular Season: Week 4 |
Panthers |
at |
 Cowboys |
Sunday, October 3, 2021 |
1:00PM |
CAR 28, DAL 36 |
| Regular Season: Week 5 |
 Eagles |
at |
Panthers |
Sunday, October 10, 2021 |
1:00PM |
PHI 21, CAR 18 |
| Regular Season: Week 6 |
 Vikings |
at |
Panthers |
Sunday, October 17, 2021 |
1:00PM |
MIN 34, CAR 28 |
| Regular Season: Week 7 |
Panthers |
at |
 Giants |
Sunday, October 24, 2021 |
1:00PM |
CAR 3, NYG 25 |
| Regular Season: Week 8 |
Panthers |
at |
 Falcons |
Sunday, October 31, 2021 |
1:00PM |
CAR 19, ATL 13 |
| Regular Season: Week 9 |
 Patriots |
at |
Panthers |
Sunday, November 7, 2021 |
1:00PM |
NE 24, CAR 6 |
| Regular Season: Week 10 |
Panthers |
at |
 Cardinals |
Sunday, November 14, 2021 |
4:05PM |
CAR 34, ARI 10 |
| Regular Season: Week 11 |
 Washington |
at |
Panthers |
Sunday, November 21, 2021 |
1:00PM |
WSH 27, CAR 21 |
| Regular Season: Week 12 |
Panthers |
at |
 Dolphins |
Sunday, November 28, 2021 |
1:00PM |
CAR 10, MIA 33 |
| Regular Season: Week 14 |
Falcons |
at |
Panthers |
Sunday, December 12, 2021 |
1:00PM |
ATL 29, CAR 21 |
| Regular Season: Week 15 |
Panthers |
at |
 Bills |
Sunday, December 19, 2021 |
TBD |
CAR 14, BUF 31 |
| Regular Season: Week 16 |
 Buccaneers |
at |
Panthers |
Sunday, December 26, 2021 |
1:00PM |
TB 32, CAR 6 |
| Regular Season: Week 17 |
Panthers |
at |
Saints |
Sunday, January 2, 2022 |
1:00PM |
CAR 10, NO 18 |
| Regular Season: Week 18 |
Panthers |
at |
Buccaneers |
Sunday, January 9, 2022 |
1:00PM |
CAR 17, TB 41 |