| Regular Season: Week 1 |
 Bengals |
at |
 Patriots |
Sunday, September 17, 1972 |
3:00PM |
CIN 31, NE 7 |
| Regular Season: Week 2 |
 Falcons |
at |
Patriots |
Sunday, September 24, 1972 |
3:00PM |
ATL 20, NE 21 |
| Regular Season: Week 3 |
 Redskins |
at |
Patriots |
Sunday, October 1, 1972 |
3:00PM |
WAS 23, NE 24 |
| Regular Season: Week 4 |
Patriots |
at |
 Bills |
Sunday, October 8, 1972 |
3:00PM |
NE 14, BUF 38 |
| Regular Season: Week 5 |
 Jets |
at |
Patriots |
Sunday, October 15, 1972 |
3:00PM |
NYJ 41, NE 13 |
| Regular Season: Week 6 |
Patriots |
at |
 Steelers |
Sunday, October 22, 1972 |
3:00PM |
NE 3, PIT 33 |
| Regular Season: Week 7 |
Patriots |
at |
Jets |
Sunday, October 29, 1972 |
2:00PM |
NE 10, NYJ 34 |
| Regular Season: Week 8 |
 Colts |
at |
Patriots |
Monday, November 6, 1972 |
3:00PM |
BAL 24, NE 17 |
| Regular Season: Week 9 |
Patriots |
at |
 Dolphins |
Sunday, November 12, 1972 |
3:00PM |
NE 0, MIA 52 |
| Regular Season: Week 10 |
Bills |
at |
Patriots |
Sunday, November 19, 1972 |
3:00PM |
BUF 27, NE 24 |
| Regular Season: Week 11 |
Patriots |
at |
Colts |
Sunday, November 26, 1972 |
3:00PM |
NE 0, BAL 31 |
| Regular Season: Week 12 |
Dolphins |
at |
Patriots |
Sunday, December 3, 1972 |
3:00PM |
MIA 37, NE 21 |
| Regular Season: Week 13 |
Patriots |
at |
 Saints |
Sunday, December 10, 1972 |
3:00PM |
NE 17, NO 10 |
| Regular Season: Week 14 |
Patriots |
at |
 Broncos |
Sunday, December 17, 1972 |
3:00PM |
NE 21, DEN 45 |