| Regular Season: Week 1 |
 Chiefs |
at |
 Patriots |
Sunday, September 7, 2008 |
1:00PM |
KC 10, NE 17 |
| Regular Season: Week 2 |
Patriots |
at |
 Jets |
Sunday, September 14, 2008 |
4:15PM |
NE 19, NYJ 10 |
| Regular Season: Week 3 |
 Dolphins |
at |
Patriots |
Sunday, September 21, 2008 |
1:00PM |
MIA 38, NE 13 |
| Regular Season: Week 5 |
Patriots |
at |
 49ers |
Sunday, October 5, 2008 |
4:15PM |
NE 30, SF 21 |
| Regular Season: Week 6 |
Patriots |
at |
 Chargers |
Sunday, October 12, 2008 |
8:15PM |
NE 10, SD 30 |
| Regular Season: Week 7 |
 Broncos |
at |
Patriots |
Monday, October 20, 2008 |
8:30PM |
DEN 7, NE 41 |
| Regular Season: Week 8 |
 Rams |
at |
Patriots |
Sunday, October 26, 2008 |
1:00PM |
STL 16, NE 23 |
| Regular Season: Week 9 |
Patriots |
at |
 Colts |
Sunday, November 2, 2008 |
8:15PM |
NE 15, IND 18 |
| Regular Season: Week 10 |
 Bills |
at |
Patriots |
Sunday, November 9, 2008 |
1:00PM |
BUF 10, NE 20 |
| Regular Season: Week 11 |
Jets |
at |
Patriots |
Thursday, November 13, 2008 |
8:15PM |
NYJ 34, NE 31 |
| Regular Season: Week 12 |
Patriots |
at |
Dolphins |
Sunday, November 23, 2008 |
1:00PM |
NE 48, MIA 28 |
| Regular Season: Week 13 |
 Steelers |
at |
Patriots |
Sunday, November 30, 2008 |
4:15PM |
PIT 33, NE 10 |
| Regular Season: Week 14 |
Patriots |
at |
 Seahawks |
Sunday, December 7, 2008 |
4:05PM |
NE 24, SEA 21 |
| Regular Season: Week 15 |
Patriots |
at |
 Raiders |
Sunday, December 14, 2008 |
4:15PM |
NE 49, OAK 26 |
| Regular Season: Week 16 |
 Cardinals |
at |
Patriots |
Sunday, December 21, 2008 |
1:00PM |
ARI 7, NE 47 |
| Regular Season: Week 17 |
Patriots |
at |
Bills |
Sunday, December 28, 2008 |
1:00PM |
NE 13, BUF 0 |