| Regular Season: Week 1 |
 Bengals |
at |
 Patriots |
Sunday, September 12, 2010 |
1:00PM |
CIN 24, NE 38 |
| Regular Season: Week 2 |
Patriots |
at |
 Jets |
Sunday, September 19, 2010 |
4:15PM |
NE 14, NYJ 28 |
| Regular Season: Week 3 |
 Bills |
at |
Patriots |
Sunday, September 26, 2010 |
1:00PM |
BUF 30, NE 38 |
| Regular Season: Week 4 |
Patriots |
at |
 Dolphins |
Monday, October 4, 2010 |
8:30PM |
NE 41, MIA 14 |
| Regular Season: Week 6 |
 Ravens |
at |
Patriots |
Sunday, October 17, 2010 |
1:00PM |
BAL 20, NE 23 |
| Regular Season: Week 7 |
Patriots |
at |
 Chargers |
Sunday, October 24, 2010 |
4:15PM |
NE 23, SD 20 |
| Regular Season: Week 8 |
 Vikings |
at |
Patriots |
Sunday, October 31, 2010 |
4:15PM |
MIN 18, NE 28 |
| Regular Season: Week 9 |
Patriots |
at |
 Browns |
Sunday, November 7, 2010 |
1:00PM |
NE 14, CLE 34 |
| Regular Season: Week 10 |
Patriots |
at |
 Steelers |
Sunday, November 14, 2010 |
8:20PM |
NE 39, PIT 26 |
| Regular Season: Week 11 |
 Colts |
at |
Patriots |
Sunday, November 21, 2010 |
4:15PM |
IND 28, NE 31 |
| Regular Season: Week 12 |
Patriots |
at |
 Lions |
Thursday, November 25, 2010 |
12:30PM |
NE 45, DET 24 |
| Regular Season: Week 13 |
Jets |
at |
Patriots |
Monday, December 6, 2010 |
8:30PM |
NYJ 3, NE 45 |
| Regular Season: Week 14 |
Patriots |
at |
 Bears |
Sunday, December 12, 2010 |
4:15PM |
NE 36, CHI 7 |
| Regular Season: Week 15 |
 Packers |
at |
Patriots |
Sunday, December 19, 2010 |
8:20PM |
GB 27, NE 31 |
| Regular Season: Week 16 |
Patriots |
at |
Bills |
Sunday, December 26, 2010 |
1:00PM |
NE 34, BUF 3 |
| Regular Season: Week 17 |
Dolphins |
at |
Patriots |
Sunday, January 2, 2011 |
1:00PM |
MIA 7, NE 38 |
| Divisional Playoffs: Week 19 |
Jets |
at |
Patriots |
Sunday, January 16, 2011 |
4:30PM |
NYJ 28, NE 21 |