| Regular Season: Week 1 |
 Ravens |
at |
 Raiders |
Monday, September 13, 2021 |
8:15PM |
BAL 27, LV 33 |
| Regular Season: Week 2 |
Raiders |
at |
 Steelers |
Sunday, September 19, 2021 |
1:00PM |
LV 26, PIT 17 |
| Regular Season: Week 3 |
 Dolphins |
at |
Raiders |
Sunday, September 26, 2021 |
4:05PM |
MIA 28, LV 31 |
| Regular Season: Week 4 |
Raiders |
at |
 Chargers |
Monday, October 4, 2021 |
8:15PM |
LV 14, LAC 28 |
| Regular Season: Week 5 |
 Bears |
at |
Raiders |
Sunday, October 10, 2021 |
4:05PM |
CHI 20, LV 9 |
| Regular Season: Week 6 |
Raiders |
at |
 Broncos |
Sunday, October 17, 2021 |
4:25PM |
LV 34, DEN 24 |
| Regular Season: Week 7 |
 Eagles |
at |
Raiders |
Sunday, October 24, 2021 |
4:05PM |
PHI 22, LV 33 |
| Regular Season: Week 9 |
Raiders |
at |
 Giants |
Sunday, November 7, 2021 |
1:00PM |
LV 16, NYG 23 |
| Regular Season: Week 10 |
 Chiefs |
at |
Raiders |
Sunday, November 14, 2021 |
8:20PM |
KC 41, LV 14 |
| Regular Season: Week 11 |
 Bengals |
at |
Raiders |
Sunday, November 21, 2021 |
4:05PM |
CIN 32, LV 13 |
| Regular Season: Week 12 |
Raiders |
at |
 Cowboys |
Thursday, November 25, 2021 |
4:30PM |
LV 36, DAL 33 |
| Regular Season: Week 13 |
 Washington |
at |
Raiders |
Sunday, December 5, 2021 |
4:05PM |
WSH 17, LV 15 |
| Regular Season: Week 14 |
Raiders |
at |
Chiefs |
Sunday, December 12, 2021 |
1:00PM |
LV 9, KC 48 |
| Regular Season: Week 15 |
Raiders |
at |
 Browns |
Sunday, December 19, 2021 |
TBD |
LV 16, CLE 14 |
| Regular Season: Week 16 |
Broncos |
at |
Raiders |
Sunday, December 26, 2021 |
4:25PM |
DEN 13, LV 17 |
| Regular Season: Week 17 |
Raiders |
at |
 Colts |
Sunday, January 2, 2022 |
1:00PM |
LV 23, IND 20 |
| Regular Season: Week 18 |
Chargers |
at |
Raiders |
Sunday, January 9, 2022 |
4:25PM |
LAC 32, LV 35 |