| Regular Season: Week 1 |
 Rams |
at |
 Packers |
Sunday, September 4, 1988 |
3:00PM |
RAM 34, GB 7 |
| Regular Season: Week 2 |
 Lions |
at |
Rams |
Sunday, September 11, 1988 |
3:00PM |
DET 10, RAM 17 |
| Regular Season: Week 3 |
Rams |
at |
 Raiders |
Sunday, September 18, 1988 |
3:00PM |
RAM 22, RAI 17 |
| Regular Season: Week 4 |
Rams |
at |
 Giants |
Sunday, September 25, 1988 |
3:00PM |
RAM 45, NYG 31 |
| Regular Season: Week 5 |
 Cardinals |
at |
Rams |
Sunday, October 2, 1988 |
3:00PM |
PHO 41, RAM 27 |
| Regular Season: Week 6 |
Rams |
at |
 Falcons |
Sunday, October 9, 1988 |
3:00PM |
RAM 33, ATL 0 |
| Regular Season: Week 7 |
 49ers |
at |
Rams |
Sunday, October 16, 1988 |
3:00PM |
SF 24, RAM 21 |
| Regular Season: Week 8 |
 Seahawks |
at |
Rams |
Sunday, October 23, 1988 |
3:00PM |
SEA 10, RAM 31 |
| Regular Season: Week 9 |
Rams |
at |
 Saints |
Sunday, October 30, 1988 |
2:00PM |
RAM 12, NO 10 |
| Regular Season: Week 10 |
Rams |
at |
 Eagles |
Sunday, November 6, 1988 |
3:00PM |
RAM 24, PHI 30 |
| Regular Season: Week 11 |
Saints |
at |
Rams |
Sunday, November 13, 1988 |
3:00PM |
NO 14, RAM 10 |
| Regular Season: Week 12 |
 Chargers |
at |
Rams |
Sunday, November 20, 1988 |
3:00PM |
SD 38, RAM 24 |
| Regular Season: Week 13 |
Rams |
at |
 Broncos |
Sunday, November 27, 1988 |
3:00PM |
RAM 24, DEN 35 |
| Regular Season: Week 14 |
 Bears |
at |
Rams |
Monday, December 5, 1988 |
3:00PM |
CHI 3, RAM 23 |
| Regular Season: Week 15 |
Falcons |
at |
Rams |
Sunday, December 11, 1988 |
3:00PM |
ATL 7, RAM 22 |
| Regular Season: Week 16 |
Rams |
at |
49ers |
Sunday, December 18, 1988 |
3:00PM |
RAM 38, SF 16 |
| Wild Card: Week 17 |
Rams |
at |
 Vikings |
Monday, December 26, 1988 |
3:00PM |
RAM 17, MIN 28 |