| Regular Season: Week 1 |
 Rams |
at |
 Eagles |
Sunday, September 7, 2008 |
1:00PM |
STL 3, PHI 38 |
| Regular Season: Week 2 |
 Giants |
at |
Rams |
Sunday, September 14, 2008 |
1:00PM |
NYG 41, STL 13 |
| Regular Season: Week 3 |
Rams |
at |
 Seahawks |
Sunday, September 21, 2008 |
4:05PM |
STL 13, SEA 37 |
| Regular Season: Week 4 |
 Bills |
at |
Rams |
Sunday, September 28, 2008 |
4:05PM |
BUF 31, STL 14 |
| Regular Season: Week 6 |
Rams |
at |
 Redskins |
Sunday, October 12, 2008 |
1:00PM |
STL 19, WAS 17 |
| Regular Season: Week 7 |
 Cowboys |
at |
Rams |
Sunday, October 19, 2008 |
1:00PM |
DAL 14, STL 34 |
| Regular Season: Week 8 |
Rams |
at |
 Patriots |
Sunday, October 26, 2008 |
1:00PM |
STL 16, NE 23 |
| Regular Season: Week 9 |
 Cardinals |
at |
Rams |
Sunday, November 2, 2008 |
1:00PM |
ARI 34, STL 13 |
| Regular Season: Week 10 |
Rams |
at |
 Jets |
Sunday, November 9, 2008 |
1:00PM |
STL 3, NYJ 47 |
| Regular Season: Week 11 |
Rams |
at |
 49ers |
Sunday, November 16, 2008 |
4:05PM |
STL 16, SF 35 |
| Regular Season: Week 12 |
 Bears |
at |
Rams |
Sunday, November 23, 2008 |
1:00PM |
CHI 27, STL 3 |
| Regular Season: Week 13 |
 Dolphins |
at |
Rams |
Sunday, November 30, 2008 |
1:00PM |
MIA 16, STL 12 |
| Regular Season: Week 14 |
Rams |
at |
Cardinals |
Sunday, December 7, 2008 |
4:15PM |
STL 10, ARI 34 |
| Regular Season: Week 15 |
Seahawks |
at |
Rams |
Sunday, December 14, 2008 |
1:00PM |
SEA 23, STL 20 |
| Regular Season: Week 16 |
49ers |
at |
Rams |
Sunday, December 21, 2008 |
1:00PM |
SF 17, STL 16 |
| Regular Season: Week 17 |
Rams |
at |
 Falcons |
Sunday, December 28, 2008 |
1:00PM |
STL 27, ATL 31 |